Explore MMP8/MMP-8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
| Target ID |
GM-T08856
|
| Target Name |
MMP8/MMP-8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4317
|
| Gene ID |
100069005 (Equus caballus), 100336575 (Bos taurus), 101080995 (Felis catus), 17394 (Mus musculus)
4317 (Homo sapiens), 489429 (Canis lupus familiaris), 63849 (Rattus norvegicus), 703536 (Macaca mulatta)
|
| Target Alternative Names |
MMP8,Mmp8,HNC,CLG1,MMP-8,PMNL-CL
|
| Uniprot Accession |
O70138,P22894,O88766
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000044786, ENSBTAG00000046732, ENSMUSG00000005800, ENSG00000118113, ENSCAFG00845000899, ENSMMUG00000004489
|
| Target Classification |
Tumor-associated antigen (TAA)
|
MMP8/MMP-8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4317 | Pre-made Human MMP8/HNC/CLG1 siRNA oligo Duplex | 4317 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo63849 | Pre-made Rat Mmp8 siRNA oligo Duplex | 63849 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17394 | Pre-made Mouse Mmp8 siRNA oligo Duplex | 17394 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703536 | Pre-made Cynomolgus/Rhesus macaque MMP8 siRNA oligo Duplex | 703536 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080995 | Pre-made Cat/Feline MMP8 siRNA oligo Duplex | 101080995 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489429 | Pre-made Dog/Canine MMP8 siRNA oligo Duplex | 489429 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336575 | Pre-made Bovines/Cattle MMP8 siRNA oligo Duplex | 100336575 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069005 | Pre-made Equine/Horse MMP8 siRNA oligo Duplex | 100069005 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MMP8/MMP-8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T08856-Ab | Human | Anti-Human MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T08856-Ab | Rat | Anti-Rat MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T08856-Ab | Mouse | Anti-Mouse MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T08856-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T08856-Ab | Cat/Feline | Anti-Cat/Feline MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T08856-Ab | Dog/Canine | Anti-Dog/Canine MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T08856-Ab | Bovines/Cattle | Anti-Bovines/Cattle MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T08856-Ab | Equine/Horse | Anti-Equine/Horse MMP8/MMP-8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MMP8/MMP-8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T08856-Ag | Human | Human MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T08856-Ag | Rat | Rat MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T08856-Ag | Mouse | Mouse MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T08856-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T08856-Ag | Cat/Feline | Cat/Feline MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T08856-Ag | Dog/Canine | Dog/Canine MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T08856-Ag | Bovines/Cattle | Bovines/Cattle MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T08856-Ag | Equine/Horse | Equine/Horse MMP8/MMP-8 recombinant protein | Mammalian cell | Detail |
