Recombinant multi-species LRRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LRRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4921513O20Rik,9330188B09Rik,AURA17,D630001M17Rik,DARDARIN,Dardarin,Gm927,LRRK2,Leucine-rich repeat serine/threonine-protein kinase 2,Lrrk2,PARK8,RIPK7,ROCO2,cI-46

Target products collectionGo to LRRK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T08123-Ag-1/ GM-Tg-hg-T08123-Ag-2 Human LRRK2 protein Human
GM-Tg-rg-T08123-Ag-1/ GM-Tg-rg-T08123-Ag-2 Rat LRRK2 protein Rat
GM-Tg-mg-T08123-Ag-1/ GM-Tg-mg-T08123-Ag-2 Mouse LRRK2 protein Mouse
GM-Tg-cynog-T08123-Ag-1/ GM-Tg-cynog-T08123-Ag-2 Cynomolgus/Rhesus macaque LRRK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T08123-Ag-1/ GM-Tg-felg-T08123-Ag-2 Feline LRRK2 protein Feline
GM-Tg-cang-T08123-Ag-1/ GM-Tg-cang-T08123-Ag-2 Canine LRRK2 protein Canine
GM-Tg-bovg-T08123-Ag-1/ GM-Tg-bovg-T08123-Ag-2 Bovine LRRK2 protein Bovine
GM-Tg-equg-T08123-Ag-1/ GM-Tg-equg-T08123-Ag-2 Equine LRRK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T08123-Ag-1/ GM-Tg-hg-T08123-Ag-2; GM-Tg-rg-T08123-Ag-1/ GM-Tg-rg-T08123-Ag-2;
GM-Tg-mg-T08123-Ag-1/ GM-Tg-mg-T08123-Ag-2; GM-Tg-cynog-T08123-Ag-1/ GM-Tg-cynog-T08123-Ag-2;
GM-Tg-felg-T08123-Ag-1/ GM-Tg-felg-T08123-Ag-2; GM-Tg-cang-T08123-Ag-1/ GM-Tg-cang-T08123-Ag-2;
GM-Tg-bovg-T08123-Ag-1/ GM-Tg-bovg-T08123-Ag-2; GM-Tg-equg-T08123-Ag-1/ GM-Tg-equg-T08123-Ag-2
Products Name LRRK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LRRK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LRRK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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