Recombinant multi-species EPO/Erythropoietin protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EPO/Erythropoietin protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
The Alternative Names of target: DBAL,ECYT5,EP,EPO,Epo,Erythropoietin,MVCD2

Target products collectionGo to EPO/Erythropoietin products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T07958-Ag-1/ GM-Tg-hg-T07958-Ag-2 Human EPO/Erythropoietin protein Human
GM-Tg-rg-T07958-Ag-1/ GM-Tg-rg-T07958-Ag-2 Rat EPO/Erythropoietin protein Rat
GM-Tg-mg-T07958-Ag-1/ GM-Tg-mg-T07958-Ag-2 Mouse EPO/Erythropoietin protein Mouse
GM-Tg-cynog-T07958-Ag-1/ GM-Tg-cynog-T07958-Ag-2 Cynomolgus/Rhesus macaque EPO/Erythropoietin protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T07958-Ag-1/ GM-Tg-felg-T07958-Ag-2 Feline EPO/Erythropoietin protein Feline
GM-Tg-cang-T07958-Ag-1/ GM-Tg-cang-T07958-Ag-2 Canine EPO/Erythropoietin protein Canine
GM-Tg-bovg-T07958-Ag-1/ GM-Tg-bovg-T07958-Ag-2 Bovine EPO/Erythropoietin protein Bovine
GM-Tg-equg-T07958-Ag-1/ GM-Tg-equg-T07958-Ag-2 Equine EPO/Erythropoietin protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T07958-Ag-1/ GM-Tg-hg-T07958-Ag-2; GM-Tg-rg-T07958-Ag-1/ GM-Tg-rg-T07958-Ag-2;
GM-Tg-mg-T07958-Ag-1/ GM-Tg-mg-T07958-Ag-2; GM-Tg-cynog-T07958-Ag-1/ GM-Tg-cynog-T07958-Ag-2;
GM-Tg-felg-T07958-Ag-1/ GM-Tg-felg-T07958-Ag-2; GM-Tg-cang-T07958-Ag-1/ GM-Tg-cang-T07958-Ag-2;
GM-Tg-bovg-T07958-Ag-1/ GM-Tg-bovg-T07958-Ag-2; GM-Tg-equg-T07958-Ag-1/ GM-Tg-equg-T07958-Ag-2
Products Name EPO/Erythropoietin protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EPO/Erythropoietin
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EPO/Erythropoietin protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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