Recombinant multi-species PAK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5330420P17Rik,A130002K10Rik,D16Ertd269e,Gamma-PAK,KNO2,PAK-2,PAK2,PAK65,PAKgamma,Pak2,S6/H4 kinase,Serine/threonine-protein kinase PAK 2,gamma-PAK,mKIAA4182,p21-activated kinase 2 (PAK-2),p58

Target products collectionGo to PAK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T07766-Ag-1/ GM-Tg-hg-T07766-Ag-2 Human PAK2 protein Human
GM-Tg-rg-T07766-Ag-1/ GM-Tg-rg-T07766-Ag-2 Rat PAK2 protein Rat
GM-Tg-mg-T07766-Ag-1/ GM-Tg-mg-T07766-Ag-2 Mouse PAK2 protein Mouse
GM-Tg-cynog-T07766-Ag-1/ GM-Tg-cynog-T07766-Ag-2 Cynomolgus/Rhesus macaque PAK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T07766-Ag-1/ GM-Tg-felg-T07766-Ag-2 Feline PAK2 protein Feline
GM-Tg-cang-T07766-Ag-1/ GM-Tg-cang-T07766-Ag-2 Canine PAK2 protein Canine
GM-Tg-bovg-T07766-Ag-1/ GM-Tg-bovg-T07766-Ag-2 Bovine PAK2 protein Bovine
GM-Tg-equg-T07766-Ag-1/ GM-Tg-equg-T07766-Ag-2 Equine PAK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T07766-Ag-1/ GM-Tg-hg-T07766-Ag-2; GM-Tg-rg-T07766-Ag-1/ GM-Tg-rg-T07766-Ag-2;
GM-Tg-mg-T07766-Ag-1/ GM-Tg-mg-T07766-Ag-2; GM-Tg-cynog-T07766-Ag-1/ GM-Tg-cynog-T07766-Ag-2;
GM-Tg-felg-T07766-Ag-1/ GM-Tg-felg-T07766-Ag-2; GM-Tg-cang-T07766-Ag-1/ GM-Tg-cang-T07766-Ag-2;
GM-Tg-bovg-T07766-Ag-1/ GM-Tg-bovg-T07766-Ag-2; GM-Tg-equg-T07766-Ag-1/ GM-Tg-equg-T07766-Ag-2
Products Name PAK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PAK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.