Recombinant multi-species MASP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MASP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
The Alternative Names of target: MAP-2,MAP19,MASP-2,MASP1P1,MASP2,MAp19,MBL-associated serine protease 2,Mannan-binding lectin serine protease 2,Mannose-binding protein-associated serine protease 2 (MASP-2),Masp2,sMAP

Target products collectionGo to MASP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T07448-Ag-1/ GM-Tg-hg-T07448-Ag-2 Human MASP2 protein Human
GM-Tg-rg-T07448-Ag-1/ GM-Tg-rg-T07448-Ag-2 Rat MASP2 protein Rat
GM-Tg-mg-T07448-Ag-1/ GM-Tg-mg-T07448-Ag-2 Mouse MASP2 protein Mouse
GM-Tg-cynog-T07448-Ag-1/ GM-Tg-cynog-T07448-Ag-2 Cynomolgus/Rhesus macaque MASP2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T07448-Ag-1/ GM-Tg-felg-T07448-Ag-2 Feline MASP2 protein Feline
GM-Tg-cang-T07448-Ag-1/ GM-Tg-cang-T07448-Ag-2 Canine MASP2 protein Canine
GM-Tg-bovg-T07448-Ag-1/ GM-Tg-bovg-T07448-Ag-2 Bovine MASP2 protein Bovine
GM-Tg-equg-T07448-Ag-1/ GM-Tg-equg-T07448-Ag-2 Equine MASP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T07448-Ag-1/ GM-Tg-hg-T07448-Ag-2; GM-Tg-rg-T07448-Ag-1/ GM-Tg-rg-T07448-Ag-2;
GM-Tg-mg-T07448-Ag-1/ GM-Tg-mg-T07448-Ag-2; GM-Tg-cynog-T07448-Ag-1/ GM-Tg-cynog-T07448-Ag-2;
GM-Tg-felg-T07448-Ag-1/ GM-Tg-felg-T07448-Ag-2; GM-Tg-cang-T07448-Ag-1/ GM-Tg-cang-T07448-Ag-2;
GM-Tg-bovg-T07448-Ag-1/ GM-Tg-bovg-T07448-Ag-2; GM-Tg-equg-T07448-Ag-1/ GM-Tg-equg-T07448-Ag-2
Products Name MASP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MASP2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MASP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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