Recombinant multi-species SOCS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AISIMD,CIS1,CISH1,Cish1,Cish7,JAB,JAK-binding protein (JAB),SOCS-1,SOCS1,SSI-1,SSI1,STAT-induced STAT inhibitor 1 (SSI-1),Socs-1,Socs1,Suppressor of cytokine signaling 1,TIP-3,TIP3,Tec-interacting protein 3 (TIP-3)

Target products collectionGo to SOCS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T06800-Ag-1/ GM-Tg-hg-T06800-Ag-2 Human SOCS1 protein Human
GM-Tg-rg-T06800-Ag-1/ GM-Tg-rg-T06800-Ag-2 Rat SOCS1 protein Rat
GM-Tg-mg-T06800-Ag-1/ GM-Tg-mg-T06800-Ag-2 Mouse SOCS1 protein Mouse
GM-Tg-cynog-T06800-Ag-1/ GM-Tg-cynog-T06800-Ag-2 Cynomolgus/Rhesus macaque SOCS1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T06800-Ag-1/ GM-Tg-felg-T06800-Ag-2 Feline SOCS1 protein Feline
GM-Tg-cang-T06800-Ag-1/ GM-Tg-cang-T06800-Ag-2 Canine SOCS1 protein Canine
GM-Tg-bovg-T06800-Ag-1/ GM-Tg-bovg-T06800-Ag-2 Bovine SOCS1 protein Bovine
GM-Tg-equg-T06800-Ag-1/ GM-Tg-equg-T06800-Ag-2 Equine SOCS1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T06800-Ag-1/ GM-Tg-hg-T06800-Ag-2; GM-Tg-rg-T06800-Ag-1/ GM-Tg-rg-T06800-Ag-2;
GM-Tg-mg-T06800-Ag-1/ GM-Tg-mg-T06800-Ag-2; GM-Tg-cynog-T06800-Ag-1/ GM-Tg-cynog-T06800-Ag-2;
GM-Tg-felg-T06800-Ag-1/ GM-Tg-felg-T06800-Ag-2; GM-Tg-cang-T06800-Ag-1/ GM-Tg-cang-T06800-Ag-2;
GM-Tg-bovg-T06800-Ag-1/ GM-Tg-bovg-T06800-Ag-2; GM-Tg-equg-T06800-Ag-1/ GM-Tg-equg-T06800-Ag-2
Products Name SOCS1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SOCS1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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