SOCS1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SOCS1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]

Target ID GM-T06800
Target Name SOCS1
Gene Group ldentifer
（Target Gene ID in Homo species) 		8651
Gene ID 102148488 (Equus caballus), 111558242 (Felis catus), 12703 (Mus musculus), 252971 (Rattus norvegicus)
490006 (Canis lupus familiaris), 518795 (Bos taurus), 711180 (Macaca mulatta), 8651 (Homo sapiens)
Target Alternative Names AISIMD,CIS1,CISH1,Cish1,Cish7,JAB,JAK-binding protein (JAB),SOCS-1,SOCS1,SSI-1,SSI1,STAT-induced STAT inhibitor 1 (SSI-1),Socs-1,Socs1,Suppressor of cytokine signaling 1,TIP-3,TIP3,Tec-interacting protein 3 (TIP-3)
Uniprot Accession O35716,Q9QX78,O15524
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Osteoclast differentiation, JAK-STAT signaling pathway, Prolactin signaling pathway, Type II diabetes mellitus, Growth hormone synthesis, secretion and action, Toxoplasmosis
Gene Ensembl ENSECAG00000026965, ENSMUSG00000038037, ENSBTAG00000004386, ENSMMUG00000010956, ENSG00000185338
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of SOCS1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP003452Human SOCS1/CIS1/CISH1 Lentivirus plasmidNM_0037458651HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000858Human SOCS1/CIS1/CISH1 Lentivirus plasmidNM_003745.18651HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000656Human SOCS1/AISIMD/CIS1 Mammalian (Non-Viral Vector) plasmidNM_003745.28651HumanMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
pGMPC001717Human SOCS1/AISIMD/CIS1 Mammalian (Non-Viral Vector) plasmidNM_003745.28651HumanMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
vGMLP003452Human SOCS1/CIS1/CISH1 Lentivirus particleNM_0037458651HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000858Human SOCS1/CIS1/CISH1 Lentivirus particleNM_003745.18651HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001458Mouse Socs1/Cish1/Cish7 Adeno-associate virus(AAV) plasmidNM_001271603.112703MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm003677Mouse Socs1/Cish1/Cish7 Lentivirus plasmidNM_001271603.112703MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC001718Mouse Socs1/Cish1/Cish7 Mammalian (Non-Viral Vector) plasmidNM_001271603.112703MouseMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
pGMPC004836Mouse Socs1/Cish1/Cish7 Mammalian (Non-Viral Vector) plasmidNM_001271603.112703MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAAV001458Mouse Socs1/Cish1/Cish7 Adeno-associate virus(AAV) particleNM_001271603.112703MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm003677Mouse Socs1/Cish1/Cish7 Lentivirus particleNM_001271603.112703MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


SOCS1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo8651Pre-made Human SOCS1/JAB/CIS1 siRNA oligo Duplex8651HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo252971Pre-made Rat Socs1/Cish1/Socs-1 siRNA oligo Duplex252971RatIn-vitro grade; in-vivo gradeDetail
pGMoligo12703Pre-made Mouse Socs1/JAB/Cish1 siRNA oligo Duplex12703MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo711180Pre-made Cynomolgus/Rhesus macaque SOCS1 siRNA oligo Duplex711180Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo111558242Pre-made Cat/Feline SOCS1 siRNA oligo Duplex111558242Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo490006Pre-made Dog/Canine SOCS1 siRNA oligo Duplex490006Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo518795Pre-made Bovines/Cattle SOCS1 siRNA oligo Duplex518795Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo102148488Pre-made Equine/Horse SOCS1 siRNA oligo Duplex102148488Equine/HorseIn-vitro grade; in-vivo gradeDetail


SOCS1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T06800-AbHumanAnti-Human SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T06800-AbRatAnti-Rat SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T06800-AbMouseAnti-Mouse SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T06800-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T06800-AbCat/FelineAnti-Cat/Feline SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T06800-AbDog/CanineAnti-Dog/Canine SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T06800-AbBovines/CattleAnti-Bovines/Cattle SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T06800-AbEquine/HorseAnti-Equine/Horse SOCS1 monoclonal antibodymabTherapeutics Target antibodyDetail


SOCS1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T06800-AgHumanHuman SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T06800-AgRatRat SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T06800-AgMouseMouse SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T06800-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T06800-AgCat/FelineCat/Feline SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T06800-AgDog/CanineDog/Canine SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T06800-AgBovines/CattleBovines/Cattle SOCS1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T06800-AgEquine/HorseEquine/Horse SOCS1 recombinant proteinMammalian cellDetail