Recombinant multi-species PARP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5830444G22Rik,ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1),ADPRT,ADPRT 1,ADPRT1,ARTD1,Adprp,Adprt,Adprt1,DNA ADP-ribosyltransferase PARP1,NAD(+) ADP-ribosyltransferase 1 (ADPRT 1),PARP,PARP-1,PARP1,PARS,PPOL,Parp-1,Parp1,Poly [ADP-ribose] polymerase 1,Poly-PARP,Poly[ADP-ribose] synthase 1,Protein poly-ADP-ribosyltransferase PARP1,msPARP,pADPRT-1,parp-1,sPARP-1

Target products collectionGo to PARP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T06273-Ag-1/ GM-Tg-hg-T06273-Ag-2 Human PARP1 protein Human
GM-Tg-rg-T06273-Ag-1/ GM-Tg-rg-T06273-Ag-2 Rat PARP1 protein Rat
GM-Tg-mg-T06273-Ag-1/ GM-Tg-mg-T06273-Ag-2 Mouse PARP1 protein Mouse
GM-Tg-cynog-T06273-Ag-1/ GM-Tg-cynog-T06273-Ag-2 Cynomolgus/Rhesus macaque PARP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T06273-Ag-1/ GM-Tg-felg-T06273-Ag-2 Feline PARP1 protein Feline
GM-Tg-cang-T06273-Ag-1/ GM-Tg-cang-T06273-Ag-2 Canine PARP1 protein Canine
GM-Tg-bovg-T06273-Ag-1/ GM-Tg-bovg-T06273-Ag-2 Bovine PARP1 protein Bovine
GM-Tg-equg-T06273-Ag-1/ GM-Tg-equg-T06273-Ag-2 Equine PARP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T06273-Ag-1/ GM-Tg-hg-T06273-Ag-2; GM-Tg-rg-T06273-Ag-1/ GM-Tg-rg-T06273-Ag-2;
GM-Tg-mg-T06273-Ag-1/ GM-Tg-mg-T06273-Ag-2; GM-Tg-cynog-T06273-Ag-1/ GM-Tg-cynog-T06273-Ag-2;
GM-Tg-felg-T06273-Ag-1/ GM-Tg-felg-T06273-Ag-2; GM-Tg-cang-T06273-Ag-1/ GM-Tg-cang-T06273-Ag-2;
GM-Tg-bovg-T06273-Ag-1/ GM-Tg-bovg-T06273-Ag-2; GM-Tg-equg-T06273-Ag-1/ GM-Tg-equg-T06273-Ag-2
Products Name PARP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PARP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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