Explore PARP1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T06273
|
| Target Name |
PARP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
142
|
| Gene ID |
100058523 (Equus caballus), 101081434 (Felis catus), 11545 (Mus musculus), 142 (Homo sapiens)
25591 (Rattus norvegicus), 286764 (Bos taurus), 490385 (Canis lupus familiaris), 698806 (Macaca mulatta)
|
| Target Alternative Names |
5830444G22Rik,ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1),ADPRT,ADPRT 1,ADPRT1,ARTD1,Adprp,Adprt,Adprt1,DNA ADP-ribosyltransferase PARP1,NAD(+) ADP-ribosyltransferase 1 (ADPRT 1),PARP,PARP-1,PARP1,PARS,PPOL,Parp-1,Parp1,Poly [ADP-ribose] polymerase 1,Poly-PARP,Poly[ADP-ribose] synthase 1,Protein poly-ADP-ribosyltransferase PARP1,msPARP,pADPRT-1,parp-1,sPARP-1
|
| Uniprot Accession |
P11103,P09874,P27008,P18493
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NF-kappa B signaling pathway, Apoptosis
|
| Gene Ensembl |
ENSECAG00000019207, ENSMUSG00000026496, ENSG00000143799, ENSBTAG00000000837, ENSCAFG00845008325, ENSMMUG00000021820
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of PARP1 cDNA Clones/ORF Plasmid
PARP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo142 | Pre-made Human PARP1/PARP/PARS siRNA oligo Duplex | 142 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25591 | Pre-made Rat Parp1/ARTD1/Adprt siRNA oligo Duplex | 25591 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11545 | Pre-made Mouse Parp1/PARP/PPOL siRNA oligo Duplex | 11545 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698806 | Pre-made Cynomolgus/Rhesus macaque PARP1 siRNA oligo Duplex | 698806 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081434 | Pre-made Cat/Feline PARP1 siRNA oligo Duplex | 101081434 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490385 | Pre-made Dog/Canine PARP1 siRNA oligo Duplex | 490385 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286764 | Pre-made Bovines/Cattle PARP1/ADPRT/ARTD1 siRNA oligo Duplex | 286764 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058523 | Pre-made Equine/Horse PARP1 siRNA oligo Duplex | 100058523 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PARP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T06273-Ab | Human | Anti-Human PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T06273-Ab | Rat | Anti-Rat PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T06273-Ab | Mouse | Anti-Mouse PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T06273-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T06273-Ab | Cat/Feline | Anti-Cat/Feline PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T06273-Ab | Dog/Canine | Anti-Dog/Canine PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T06273-Ab | Bovines/Cattle | Anti-Bovines/Cattle PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T06273-Ab | Equine/Horse | Anti-Equine/Horse PARP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PARP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T06273-Ag | Human | Human PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T06273-Ag | Rat | Rat PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T06273-Ag | Mouse | Mouse PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T06273-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T06273-Ag | Cat/Feline | Cat/Feline PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T06273-Ag | Dog/Canine | Dog/Canine PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T06273-Ag | Bovines/Cattle | Bovines/Cattle PARP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T06273-Ag | Equine/Horse | Equine/Horse PARP1 recombinant protein | Mammalian cell | Detail |
