Recombinant multi-species IRS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IRS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4PS,IRS-2,IRS2,Insulin receptor substrate 2,Irs-2,Irs2

Target products collectionGo to IRS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T06128-Ag-1/ GM-Tg-hg-T06128-Ag-2 Human IRS2 protein Human
GM-Tg-rg-T06128-Ag-1/ GM-Tg-rg-T06128-Ag-2 Rat IRS2 protein Rat
GM-Tg-mg-T06128-Ag-1/ GM-Tg-mg-T06128-Ag-2 Mouse IRS2 protein Mouse
GM-Tg-cynog-T06128-Ag-1/ GM-Tg-cynog-T06128-Ag-2 Cynomolgus/Rhesus macaque IRS2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T06128-Ag-1/ GM-Tg-felg-T06128-Ag-2 Feline IRS2 protein Feline
GM-Tg-cang-T06128-Ag-1/ GM-Tg-cang-T06128-Ag-2 Canine IRS2 protein Canine
GM-Tg-bovg-T06128-Ag-1/ GM-Tg-bovg-T06128-Ag-2 Bovine IRS2 protein Bovine
GM-Tg-equg-T06128-Ag-1/ GM-Tg-equg-T06128-Ag-2 Equine IRS2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T06128-Ag-1/ GM-Tg-hg-T06128-Ag-2; GM-Tg-rg-T06128-Ag-1/ GM-Tg-rg-T06128-Ag-2;
GM-Tg-mg-T06128-Ag-1/ GM-Tg-mg-T06128-Ag-2; GM-Tg-cynog-T06128-Ag-1/ GM-Tg-cynog-T06128-Ag-2;
GM-Tg-felg-T06128-Ag-1/ GM-Tg-felg-T06128-Ag-2; GM-Tg-cang-T06128-Ag-1/ GM-Tg-cang-T06128-Ag-2;
GM-Tg-bovg-T06128-Ag-1/ GM-Tg-bovg-T06128-Ag-2; GM-Tg-equg-T06128-Ag-1/ GM-Tg-equg-T06128-Ag-2
Products Name IRS2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IRS2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IRS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.