Recombinant multi-species PI3 Kinase p110 Beta/PIK3CB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PI3 Kinase p110 Beta/PIK3CB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
The Alternative Names of target: 1110001J02Rik,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta (PtdIns-3-kinase subunit p110-beta,5-bisphosphate 3-kinase catalytic subunit beta isoform,P110BETA,PI3 Kinase p110 Beta,PI3-kinase subunit beta,PI3K,PI3K-beta,PI3KBETA,PI3Kbeta,PIK3C1,PIK3CB,Phosphatidylinositol 4,Pik3cb,PtdIns-3-kinase subunit beta,Serine/threonine protein kinase PIK3CB,p110beta,p110beta)
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T05031-Ag-1/ GM-Tg-hg-T05031-Ag-2 | Human PI3 Kinase p110 Beta/PIK3CB protein | Human |
| GM-Tg-rg-T05031-Ag-1/ GM-Tg-rg-T05031-Ag-2 | Rat PI3 Kinase p110 Beta/PIK3CB protein | Rat |
| GM-Tg-mg-T05031-Ag-1/ GM-Tg-mg-T05031-Ag-2 | Mouse PI3 Kinase p110 Beta/PIK3CB protein | Mouse |
| GM-Tg-cynog-T05031-Ag-1/ GM-Tg-cynog-T05031-Ag-2 | Cynomolgus/Rhesus macaque PI3 Kinase p110 Beta/PIK3CB protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T05031-Ag-1/ GM-Tg-felg-T05031-Ag-2 | Feline PI3 Kinase p110 Beta/PIK3CB protein | Feline |
| GM-Tg-cang-T05031-Ag-1/ GM-Tg-cang-T05031-Ag-2 | Canine PI3 Kinase p110 Beta/PIK3CB protein | Canine |
| GM-Tg-bovg-T05031-Ag-1/ GM-Tg-bovg-T05031-Ag-2 | Bovine PI3 Kinase p110 Beta/PIK3CB protein | Bovine |
| GM-Tg-equg-T05031-Ag-1/ GM-Tg-equg-T05031-Ag-2 | Equine PI3 Kinase p110 Beta/PIK3CB protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T05031-Ag-1/ GM-Tg-hg-T05031-Ag-2;
GM-Tg-rg-T05031-Ag-1/ GM-Tg-rg-T05031-Ag-2;
GM-Tg-mg-T05031-Ag-1/ GM-Tg-mg-T05031-Ag-2; GM-Tg-cynog-T05031-Ag-1/ GM-Tg-cynog-T05031-Ag-2; GM-Tg-felg-T05031-Ag-1/ GM-Tg-felg-T05031-Ag-2; GM-Tg-cang-T05031-Ag-1/ GM-Tg-cang-T05031-Ag-2; GM-Tg-bovg-T05031-Ag-1/ GM-Tg-bovg-T05031-Ag-2; GM-Tg-equg-T05031-Ag-1/ GM-Tg-equg-T05031-Ag-2 |
| Products Name | PI3 Kinase p110 Beta/PIK3CB protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PI3 Kinase p110 Beta/PIK3CB |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PI3 Kinase p110 Beta/PIK3CB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.