Recombinant multi-species CAPN2/Calpain 2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CAPN2/Calpain 2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
The Alternative Names of target: CALP80,CANP2,CANPL2,CANPml,CAPN2,Calcium-activated neutral proteinase 2 (CANP 2),Calpain 2,Calpain M-type,Calpain large polypeptide L2,Calpain-2 catalytic subunit,Calpain-2 large subunit,Capa-2,Capa2,Capn2,Millimolar-calpain (M-calpain),m-calpain,m-calpin,mCANP
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T04902-Ag-1/ GM-Tg-hg-T04902-Ag-2 | Human CAPN2/Calpain 2 protein | Human |
| GM-Tg-rg-T04902-Ag-1/ GM-Tg-rg-T04902-Ag-2 | Rat CAPN2/Calpain 2 protein | Rat |
| GM-Tg-mg-T04902-Ag-1/ GM-Tg-mg-T04902-Ag-2 | Mouse CAPN2/Calpain 2 protein | Mouse |
| GM-Tg-cynog-T04902-Ag-1/ GM-Tg-cynog-T04902-Ag-2 | Cynomolgus/Rhesus macaque CAPN2/Calpain 2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T04902-Ag-1/ GM-Tg-felg-T04902-Ag-2 | Feline CAPN2/Calpain 2 protein | Feline |
| GM-Tg-cang-T04902-Ag-1/ GM-Tg-cang-T04902-Ag-2 | Canine CAPN2/Calpain 2 protein | Canine |
| GM-Tg-bovg-T04902-Ag-1/ GM-Tg-bovg-T04902-Ag-2 | Bovine CAPN2/Calpain 2 protein | Bovine |
| GM-Tg-equg-T04902-Ag-1/ GM-Tg-equg-T04902-Ag-2 | Equine CAPN2/Calpain 2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T04902-Ag-1/ GM-Tg-hg-T04902-Ag-2;
GM-Tg-rg-T04902-Ag-1/ GM-Tg-rg-T04902-Ag-2;
GM-Tg-mg-T04902-Ag-1/ GM-Tg-mg-T04902-Ag-2; GM-Tg-cynog-T04902-Ag-1/ GM-Tg-cynog-T04902-Ag-2; GM-Tg-felg-T04902-Ag-1/ GM-Tg-felg-T04902-Ag-2; GM-Tg-cang-T04902-Ag-1/ GM-Tg-cang-T04902-Ag-2; GM-Tg-bovg-T04902-Ag-1/ GM-Tg-bovg-T04902-Ag-2; GM-Tg-equg-T04902-Ag-1/ GM-Tg-equg-T04902-Ag-2 |
| Products Name | CAPN2/Calpain 2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CAPN2/Calpain 2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CAPN2/Calpain 2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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