Explore CAPN2/Calpain 2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| Target ID |
GM-T04902
|
| Target Name |
CAPN2/Calpain 2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
824
|
| Gene ID |
100055184 (Equus caballus), 101083231 (Felis catus), 12334 (Mus musculus), 281662 (Bos taurus) 29154 (Rattus norvegicus), 480118 (Canis lupus familiaris), 703047 (Macaca mulatta), 824 (Homo sapiens)
|
| Target Alternative Names |
CALP80,CANP2,CANPL2,CANPml,CAPN2,Calcium-activated neutral proteinase 2 (CANP 2),Calpain 2,Calpain M-type,Calpain large polypeptide L2,Calpain-2 catalytic subunit,Calpain-2 large subunit,Capa-2,Capa2,Capn2,Millimolar-calpain (M-calpain),m-calpain,m-calpin,mCANP
|
| Uniprot Accession |
O08529,Q27971,Q07009,P17655
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, Apoptosis, Cellular senescence, Focal adhesion, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000008742, ENSMUSG00000026509, ENSBTAG00000012778, ENSCAFG00845013136, ENSMMUG00000011142, ENSG00000162909
|
Pre-made viral vector of CAPN2/Calpain 2 cDNA Clones/ORF Plasmid
CAPN2/Calpain 2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo824 | Pre-made Human CAPN2/CANP2/mCANP siRNA oligo Duplex | 824 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29154 | Pre-made Rat Capn2 siRNA oligo Duplex | 29154 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12334 | Pre-made Mouse Capn2/Capa2/CALP80 siRNA oligo Duplex | 12334 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703047 | Pre-made Cynomolgus/Rhesus macaque CAPN2 siRNA oligo Duplex | 703047 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083231 | Pre-made Cat/Feline CAPN2 siRNA oligo Duplex | 101083231 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480118 | Pre-made Dog/Canine CAPN2 siRNA oligo Duplex | 480118 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281662 | Pre-made Bovines/Cattle CAPN2 siRNA oligo Duplex | 281662 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055184 | Pre-made Equine/Horse CAPN2 siRNA oligo Duplex | 100055184 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CAPN2/Calpain 2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T04902-Ab | Human | Anti-Human CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T04902-Ab | Rat | Anti-Rat CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T04902-Ab | Mouse | Anti-Mouse CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T04902-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T04902-Ab | Cat/Feline | Anti-Cat/Feline CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T04902-Ab | Dog/Canine | Anti-Dog/Canine CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T04902-Ab | Bovines/Cattle | Anti-Bovines/Cattle CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T04902-Ab | Equine/Horse | Anti-Equine/Horse CAPN2/Calpain 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CAPN2/Calpain 2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T04902-Ag | Human | Human CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T04902-Ag | Rat | Rat CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T04902-Ag | Mouse | Mouse CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T04902-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T04902-Ag | Cat/Feline | Cat/Feline CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T04902-Ag | Dog/Canine | Dog/Canine CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T04902-Ag | Bovines/Cattle | Bovines/Cattle CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T04902-Ag | Equine/Horse | Equine/Horse CAPN2/Calpain 2 recombinant protein | Mammalian cell | Detail |