Recombinant multi-species HNF1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNF1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
The Alternative Names of target: HNF-1-alpha,HNF-1A,HNF-1a,HNF1,HNF1-alpha,HNF1A,HNF1[a],HNF1alpha,HNF4A,Hepatocyte nuclear factor 1-alpha,Hnf-1,Hnf1a,Hnf1alpha,IDDM20,LF-B1,LFB1,Lfb1,Liver-specific transcription factor LF-B1 (LFB1),MODY3,TCF-1,TCF1,Tcf-1,Tcf1,Transcription factor 1 (TCF-1)

Target products collectionGo to HNF1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T03556-Ag-1/ GM-Tg-hg-T03556-Ag-2 Human HNF1A protein Human
GM-Tg-rg-T03556-Ag-1/ GM-Tg-rg-T03556-Ag-2 Rat HNF1A protein Rat
GM-Tg-mg-T03556-Ag-1/ GM-Tg-mg-T03556-Ag-2 Mouse HNF1A protein Mouse
GM-Tg-cynog-T03556-Ag-1/ GM-Tg-cynog-T03556-Ag-2 Cynomolgus/Rhesus macaque HNF1A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T03556-Ag-1/ GM-Tg-felg-T03556-Ag-2 Feline HNF1A protein Feline
GM-Tg-cang-T03556-Ag-1/ GM-Tg-cang-T03556-Ag-2 Canine HNF1A protein Canine
GM-Tg-bovg-T03556-Ag-1/ GM-Tg-bovg-T03556-Ag-2 Bovine HNF1A protein Bovine
GM-Tg-equg-T03556-Ag-1/ GM-Tg-equg-T03556-Ag-2 Equine HNF1A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T03556-Ag-1/ GM-Tg-hg-T03556-Ag-2; GM-Tg-rg-T03556-Ag-1/ GM-Tg-rg-T03556-Ag-2;
GM-Tg-mg-T03556-Ag-1/ GM-Tg-mg-T03556-Ag-2; GM-Tg-cynog-T03556-Ag-1/ GM-Tg-cynog-T03556-Ag-2;
GM-Tg-felg-T03556-Ag-1/ GM-Tg-felg-T03556-Ag-2; GM-Tg-cang-T03556-Ag-1/ GM-Tg-cang-T03556-Ag-2;
GM-Tg-bovg-T03556-Ag-1/ GM-Tg-bovg-T03556-Ag-2; GM-Tg-equg-T03556-Ag-1/ GM-Tg-equg-T03556-Ag-2
Products Name HNF1A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HNF1A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNF1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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