Recombinant multi-species MMP12/MMP-12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP12/MMP-12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
The Alternative Names of target: HME,ME,MME,MMP-12,MMP12,Macrophage elastase (ME,Macrophage metalloelastase,Matrix metalloproteinase-12 (MMP-12),Mme,Mmel,Mmp12,hME)

Target products collectionGo to MMP12/MMP-12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T03500-Ag-1/ GM-Tg-hg-T03500-Ag-2 Human MMP12/MMP-12 protein Human
GM-Tg-rg-T03500-Ag-1/ GM-Tg-rg-T03500-Ag-2 Rat MMP12/MMP-12 protein Rat
GM-Tg-mg-T03500-Ag-1/ GM-Tg-mg-T03500-Ag-2 Mouse MMP12/MMP-12 protein Mouse
GM-Tg-cynog-T03500-Ag-1/ GM-Tg-cynog-T03500-Ag-2 Cynomolgus/Rhesus macaque MMP12/MMP-12 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T03500-Ag-1/ GM-Tg-felg-T03500-Ag-2 Feline MMP12/MMP-12 protein Feline
GM-Tg-cang-T03500-Ag-1/ GM-Tg-cang-T03500-Ag-2 Canine MMP12/MMP-12 protein Canine
GM-Tg-bovg-T03500-Ag-1/ GM-Tg-bovg-T03500-Ag-2 Bovine MMP12/MMP-12 protein Bovine
GM-Tg-equg-T03500-Ag-1/ GM-Tg-equg-T03500-Ag-2 Equine MMP12/MMP-12 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T03500-Ag-1/ GM-Tg-hg-T03500-Ag-2; GM-Tg-rg-T03500-Ag-1/ GM-Tg-rg-T03500-Ag-2;
GM-Tg-mg-T03500-Ag-1/ GM-Tg-mg-T03500-Ag-2; GM-Tg-cynog-T03500-Ag-1/ GM-Tg-cynog-T03500-Ag-2;
GM-Tg-felg-T03500-Ag-1/ GM-Tg-felg-T03500-Ag-2; GM-Tg-cang-T03500-Ag-1/ GM-Tg-cang-T03500-Ag-2;
GM-Tg-bovg-T03500-Ag-1/ GM-Tg-bovg-T03500-Ag-2; GM-Tg-equg-T03500-Ag-1/ GM-Tg-equg-T03500-Ag-2
Products Name MMP12/MMP-12 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MMP12/MMP-12
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP12/MMP-12 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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