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Recombinant multi-species IFN beta/IFN beta1/IFNB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFN beta/IFN beta1/IFNB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
The Alternative Names of target: Fibroblast interferon,IF1DA1,IFB,IFF,IFN beta,IFN beta1,IFN-beta,IFNB,IFNB1,If1da1,Ifb,Ifnb,Ifnb1,Interferon beta
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MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T02808-Ag-1/ GM-Tg-hg-T02808-Ag-2 | Human IFN beta/IFN beta1/IFNB1 protein | Human |
| GM-Tg-rg-T02808-Ag-1/ GM-Tg-rg-T02808-Ag-2 | Rat IFN beta/IFN beta1/IFNB1 protein | Rat |
| GM-Tg-mg-T02808-Ag-1/ GM-Tg-mg-T02808-Ag-2 | Mouse IFN beta/IFN beta1/IFNB1 protein | Mouse |
| GM-Tg-cynog-T02808-Ag-1/ GM-Tg-cynog-T02808-Ag-2 | Cynomolgus/Rhesus macaque IFN beta/IFN beta1/IFNB1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T02808-Ag-1/ GM-Tg-felg-T02808-Ag-2 | Feline IFN beta/IFN beta1/IFNB1 protein | Feline |
| GM-Tg-cang-T02808-Ag-1/ GM-Tg-cang-T02808-Ag-2 | Canine IFN beta/IFN beta1/IFNB1 protein | Canine |
| GM-Tg-bovg-T02808-Ag-1/ GM-Tg-bovg-T02808-Ag-2 | Bovine IFN beta/IFN beta1/IFNB1 protein | Bovine |
| GM-Tg-equg-T02808-Ag-1/ GM-Tg-equg-T02808-Ag-2 | Equine IFN beta/IFN beta1/IFNB1 protein | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T02808-Ag-1/ GM-Tg-hg-T02808-Ag-2;
GM-Tg-rg-T02808-Ag-1/ GM-Tg-rg-T02808-Ag-2;
GM-Tg-mg-T02808-Ag-1/ GM-Tg-mg-T02808-Ag-2; GM-Tg-cynog-T02808-Ag-1/ GM-Tg-cynog-T02808-Ag-2; GM-Tg-felg-T02808-Ag-1/ GM-Tg-felg-T02808-Ag-2; GM-Tg-cang-T02808-Ag-1/ GM-Tg-cang-T02808-Ag-2; GM-Tg-bovg-T02808-Ag-1/ GM-Tg-bovg-T02808-Ag-2; GM-Tg-equg-T02808-Ag-1/ GM-Tg-equg-T02808-Ag-2 |
| Products Name | IFN beta/IFN beta1/IFNB1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | IFN beta/IFN beta1/IFNB1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFN beta/IFN beta1/IFNB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.