Recombinant multi-species SURVIVIN/BIRC5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SURVIVIN/BIRC5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
The Alternative Names of target: AAC-11,AP14,API4,Api4,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,BIRC5,Baculoviral IAP repeat-containing protein 5,Birc5,EPR-1,SURVIVIN,TIAP,survivin40
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T02677-Ag-1/ GM-Tg-hg-T02677-Ag-2 | Human SURVIVIN/BIRC5 protein | Human |
| GM-Tg-rg-T02677-Ag-1/ GM-Tg-rg-T02677-Ag-2 | Rat SURVIVIN/BIRC5 protein | Rat |
| GM-Tg-mg-T02677-Ag-1/ GM-Tg-mg-T02677-Ag-2 | Mouse SURVIVIN/BIRC5 protein | Mouse |
| GM-Tg-cynog-T02677-Ag-1/ GM-Tg-cynog-T02677-Ag-2 | Cynomolgus/Rhesus macaque SURVIVIN/BIRC5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T02677-Ag-1/ GM-Tg-felg-T02677-Ag-2 | Feline SURVIVIN/BIRC5 protein | Feline |
| GM-Tg-cang-T02677-Ag-1/ GM-Tg-cang-T02677-Ag-2 | Canine SURVIVIN/BIRC5 protein | Canine |
| GM-Tg-bovg-T02677-Ag-1/ GM-Tg-bovg-T02677-Ag-2 | Bovine SURVIVIN/BIRC5 protein | Bovine |
| GM-Tg-equg-T02677-Ag-1/ GM-Tg-equg-T02677-Ag-2 | Equine SURVIVIN/BIRC5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T02677-Ag-1/ GM-Tg-hg-T02677-Ag-2;
GM-Tg-rg-T02677-Ag-1/ GM-Tg-rg-T02677-Ag-2;
GM-Tg-mg-T02677-Ag-1/ GM-Tg-mg-T02677-Ag-2; GM-Tg-cynog-T02677-Ag-1/ GM-Tg-cynog-T02677-Ag-2; GM-Tg-felg-T02677-Ag-1/ GM-Tg-felg-T02677-Ag-2; GM-Tg-cang-T02677-Ag-1/ GM-Tg-cang-T02677-Ag-2; GM-Tg-bovg-T02677-Ag-1/ GM-Tg-bovg-T02677-Ag-2; GM-Tg-equg-T02677-Ag-1/ GM-Tg-equg-T02677-Ag-2 |
| Products Name | SURVIVIN/BIRC5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SURVIVIN/BIRC5 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SURVIVIN/BIRC5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
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Through
expression in mammalian cell lines, GMab has
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myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.