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Recombinant multi-species PKC Epsilon/PRKCE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKC Epsilon/PRKCE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5830406C15Rik,PKC Epsilon,PKCE,PKC[e],PKCepsilon,PRKCE,Pkce,Prkce,Protein kinase C epsilon type,nPKC-epsilon
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MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T00895-Ag-1/ GM-Tg-hg-T00895-Ag-2 | Human PKC Epsilon/PRKCE protein | Human |
| GM-Tg-rg-T00895-Ag-1/ GM-Tg-rg-T00895-Ag-2 | Rat PKC Epsilon/PRKCE protein | Rat |
| GM-Tg-mg-T00895-Ag-1/ GM-Tg-mg-T00895-Ag-2 | Mouse PKC Epsilon/PRKCE protein | Mouse |
| GM-Tg-cynog-T00895-Ag-1/ GM-Tg-cynog-T00895-Ag-2 | Cynomolgus/Rhesus macaque PKC Epsilon/PRKCE protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T00895-Ag-1/ GM-Tg-felg-T00895-Ag-2 | Feline PKC Epsilon/PRKCE protein | Feline |
| GM-Tg-cang-T00895-Ag-1/ GM-Tg-cang-T00895-Ag-2 | Canine PKC Epsilon/PRKCE protein | Canine |
| GM-Tg-bovg-T00895-Ag-1/ GM-Tg-bovg-T00895-Ag-2 | Bovine PKC Epsilon/PRKCE protein | Bovine |
| GM-Tg-equg-T00895-Ag-1/ GM-Tg-equg-T00895-Ag-2 | Equine PKC Epsilon/PRKCE protein | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T00895-Ag-1/ GM-Tg-hg-T00895-Ag-2;
GM-Tg-rg-T00895-Ag-1/ GM-Tg-rg-T00895-Ag-2;
GM-Tg-mg-T00895-Ag-1/ GM-Tg-mg-T00895-Ag-2; GM-Tg-cynog-T00895-Ag-1/ GM-Tg-cynog-T00895-Ag-2; GM-Tg-felg-T00895-Ag-1/ GM-Tg-felg-T00895-Ag-2; GM-Tg-cang-T00895-Ag-1/ GM-Tg-cang-T00895-Ag-2; GM-Tg-bovg-T00895-Ag-1/ GM-Tg-bovg-T00895-Ag-2; GM-Tg-equg-T00895-Ag-1/ GM-Tg-equg-T00895-Ag-2 |
| Products Name | PKC Epsilon/PRKCE protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PKC Epsilon/PRKCE |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKC Epsilon/PRKCE protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
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Through
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been established as a paradigmatic
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myriad domains of biological drug
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.