Recombinant multi-species JNK/MAPK10/JNK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine JNK/MAPK10/JNK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
The Alternative Names of target: C230008H04Rik,JNK,JNK3,JNK3A,JNK3B1,JNK3B2,Jnk3,MAP kinase 10,MAP kinase p49 3F12,MAPK 10,MAPK10,Mapk10,Mitogen-activated protein kinase 10,PRKM10,SAPK(beta),SAPK1b,SAPKC,SAPb,Serk2,Stress-activated protein kinase 1b (SAPK1b),Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3,p493F12,p54bSAPK

Target products collectionGo to JNK/MAPK10/JNK3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T00663-Ag-1/ GM-Tg-hg-T00663-Ag-2 Human JNK/MAPK10/JNK3 protein Human
GM-Tg-rg-T00663-Ag-1/ GM-Tg-rg-T00663-Ag-2 Rat JNK/MAPK10/JNK3 protein Rat
GM-Tg-mg-T00663-Ag-1/ GM-Tg-mg-T00663-Ag-2 Mouse JNK/MAPK10/JNK3 protein Mouse
GM-Tg-cynog-T00663-Ag-1/ GM-Tg-cynog-T00663-Ag-2 Cynomolgus/Rhesus macaque JNK/MAPK10/JNK3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T00663-Ag-1/ GM-Tg-felg-T00663-Ag-2 Feline JNK/MAPK10/JNK3 protein Feline
GM-Tg-cang-T00663-Ag-1/ GM-Tg-cang-T00663-Ag-2 Canine JNK/MAPK10/JNK3 protein Canine
GM-Tg-bovg-T00663-Ag-1/ GM-Tg-bovg-T00663-Ag-2 Bovine JNK/MAPK10/JNK3 protein Bovine
GM-Tg-equg-T00663-Ag-1/ GM-Tg-equg-T00663-Ag-2 Equine JNK/MAPK10/JNK3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T00663-Ag-1/ GM-Tg-hg-T00663-Ag-2; GM-Tg-rg-T00663-Ag-1/ GM-Tg-rg-T00663-Ag-2;
GM-Tg-mg-T00663-Ag-1/ GM-Tg-mg-T00663-Ag-2; GM-Tg-cynog-T00663-Ag-1/ GM-Tg-cynog-T00663-Ag-2;
GM-Tg-felg-T00663-Ag-1/ GM-Tg-felg-T00663-Ag-2; GM-Tg-cang-T00663-Ag-1/ GM-Tg-cang-T00663-Ag-2;
GM-Tg-bovg-T00663-Ag-1/ GM-Tg-bovg-T00663-Ag-2; GM-Tg-equg-T00663-Ag-1/ GM-Tg-equg-T00663-Ag-2
Products Name JNK/MAPK10/JNK3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name JNK/MAPK10/JNK3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine JNK/MAPK10/JNK3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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