Recombinant multi-species PDI/P4HB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDI/P4HB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CLCRP1,Cellular thyroid hormone-binding protein,DSI,ERBA2L,ERp59,GIT,P4HB,P4Hbeta,P4hb,PDI,PDIA1,PDIR,PHDB,PO4DB,PO4HB,PROHB,Pdia1,Prolyl 4-hydroxylase subunit beta,Protein disulfide-isomerase,Thbp,p55

Target products collectionGo to PDI/P4HB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1636-Ag-1/ GM-Tg-hg-SE1636-Ag-2 Human PDI/P4HB protein Human
GM-Tg-rg-SE1636-Ag-1/ GM-Tg-rg-SE1636-Ag-2 Rat PDI/P4HB protein Rat
GM-Tg-mg-SE1636-Ag-1/ GM-Tg-mg-SE1636-Ag-2 Mouse PDI/P4HB protein Mouse
GM-Tg-cynog-SE1636-Ag-1/ GM-Tg-cynog-SE1636-Ag-2 Cynomolgus/Rhesus macaque PDI/P4HB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1636-Ag-1/ GM-Tg-felg-SE1636-Ag-2 Feline PDI/P4HB protein Feline
GM-Tg-cang-SE1636-Ag-1/ GM-Tg-cang-SE1636-Ag-2 Canine PDI/P4HB protein Canine
GM-Tg-bovg-SE1636-Ag-1/ GM-Tg-bovg-SE1636-Ag-2 Bovine PDI/P4HB protein Bovine
GM-Tg-equg-SE1636-Ag-1/ GM-Tg-equg-SE1636-Ag-2 Equine PDI/P4HB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1636-Ag-1/ GM-Tg-hg-SE1636-Ag-2; GM-Tg-rg-SE1636-Ag-1/ GM-Tg-rg-SE1636-Ag-2;
GM-Tg-mg-SE1636-Ag-1/ GM-Tg-mg-SE1636-Ag-2; GM-Tg-cynog-SE1636-Ag-1/ GM-Tg-cynog-SE1636-Ag-2;
GM-Tg-felg-SE1636-Ag-1/ GM-Tg-felg-SE1636-Ag-2; GM-Tg-cang-SE1636-Ag-1/ GM-Tg-cang-SE1636-Ag-2;
GM-Tg-bovg-SE1636-Ag-1/ GM-Tg-bovg-SE1636-Ag-2; GM-Tg-equg-SE1636-Ag-1/ GM-Tg-equg-SE1636-Ag-2
Products Name PDI/P4HB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PDI/P4HB
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDI/P4HB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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