Recombinant multi-species GLUD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GLUD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
The Alternative Names of target: Ac2-281,GDH,GDH 1,GDH1,GLUD,GLUD1,Gdh-X,Gdh1,Glud,Glud1,Gludeha,Gludl,Glutamate dehydrogenase 1,MRG-2,hGDH1,mitochondrial

Target products collectionGo to GLUD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1537-Ag-1/ GM-Tg-hg-SE1537-Ag-2 Human GLUD1 protein Human
GM-Tg-rg-SE1537-Ag-1/ GM-Tg-rg-SE1537-Ag-2 Rat GLUD1 protein Rat
GM-Tg-mg-SE1537-Ag-1/ GM-Tg-mg-SE1537-Ag-2 Mouse GLUD1 protein Mouse
GM-Tg-cynog-SE1537-Ag-1/ GM-Tg-cynog-SE1537-Ag-2 Cynomolgus/Rhesus macaque GLUD1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1537-Ag-1/ GM-Tg-felg-SE1537-Ag-2 Feline GLUD1 protein Feline
GM-Tg-cang-SE1537-Ag-1/ GM-Tg-cang-SE1537-Ag-2 Canine GLUD1 protein Canine
GM-Tg-bovg-SE1537-Ag-1/ GM-Tg-bovg-SE1537-Ag-2 Bovine GLUD1 protein Bovine
GM-Tg-equg-SE1537-Ag-1/ GM-Tg-equg-SE1537-Ag-2 Equine GLUD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1537-Ag-1/ GM-Tg-hg-SE1537-Ag-2; GM-Tg-rg-SE1537-Ag-1/ GM-Tg-rg-SE1537-Ag-2;
GM-Tg-mg-SE1537-Ag-1/ GM-Tg-mg-SE1537-Ag-2; GM-Tg-cynog-SE1537-Ag-1/ GM-Tg-cynog-SE1537-Ag-2;
GM-Tg-felg-SE1537-Ag-1/ GM-Tg-felg-SE1537-Ag-2; GM-Tg-cang-SE1537-Ag-1/ GM-Tg-cang-SE1537-Ag-2;
GM-Tg-bovg-SE1537-Ag-1/ GM-Tg-bovg-SE1537-Ag-2; GM-Tg-equg-SE1537-Ag-1/ GM-Tg-equg-SE1537-Ag-2
Products Name GLUD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GLUD1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GLUD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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