Explore GLUD1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
| Target ID |
GM-SE1537
|
| Target Name |
GLUD1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2746
|
| Gene ID |
100064139 (Equus caballus), 100684847 (Canis lupus familiaris), 101090049 (Felis catus), 14661 (Mus musculus)
24399 (Rattus norvegicus), 2746 (Homo sapiens), 281785 (Bos taurus), 693461 (Macaca mulatta)
|
| Target Alternative Names |
Ac2-281,GDH,GDH 1,GDH1,GLUD,GLUD1,Gdh-X,Gdh1,Glud,Glud1,Gludeha,Gludl,Glutamate dehydrogenase 1,MRG-2,hGDH1,mitochondrial
|
| Uniprot Accession |
P26443,P10860,P00367,P00366
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000007371, ENSCAFG00845007152, ENSMUSG00000021794, ENSG00000148672, ENSBTAG00000007540, ENSMMUG00000022075
|
GLUD1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2746 | Pre-made Human GLUD1/GDH/GDH1 siRNA oligo Duplex | 2746 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24399 | Pre-made Rat Glud1/Gdh1/Glud siRNA oligo Duplex | 24399 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14661 | Pre-made Mouse Glud1/Glud/Gdh-X siRNA oligo Duplex | 14661 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693461 | Pre-made Cynomolgus/Rhesus macaque GLUD1 siRNA oligo Duplex | 693461 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090049 | Pre-made Cat/Feline GLUD1 siRNA oligo Duplex | 101090049 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100684847 | Pre-made Dog/Canine GLUD1 siRNA oligo Duplex | 100684847 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281785 | Pre-made Bovines/Cattle GLUD1/GDH/GDH1 siRNA oligo Duplex | 281785 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064139 | Pre-made Equine/Horse GLUD1 siRNA oligo Duplex | 100064139 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GLUD1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1537-Ab | Human | Anti-Human GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1537-Ab | Rat | Anti-Rat GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1537-Ab | Mouse | Anti-Mouse GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1537-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1537-Ab | Cat/Feline | Anti-Cat/Feline GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1537-Ab | Dog/Canine | Anti-Dog/Canine GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1537-Ab | Bovines/Cattle | Anti-Bovines/Cattle GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1537-Ab | Equine/Horse | Anti-Equine/Horse GLUD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GLUD1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1537-Ag | Human | Human GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1537-Ag | Rat | Rat GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1537-Ag | Mouse | Mouse GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1537-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1537-Ag | Cat/Feline | Cat/Feline GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1537-Ag | Dog/Canine | Dog/Canine GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1537-Ag | Bovines/Cattle | Bovines/Cattle GLUD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1537-Ag | Equine/Horse | Equine/Horse GLUD1 recombinant protein | Mammalian cell | Detail |
