Recombinant multi-species BMAL1/ARNTL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BMAL1/ARNTL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021]
The Alternative Names of target: ARNTL,ARNTL1,Arnt3,Arntl,Aryl hydrocarbon receptor nuclear translocator-like protein 1,BMAL1,BMAL1b,BMAL1c,Basic helix-loop-helix ARNT-like protein 1,Basic-helix-loop-helix-PAS protein MOP3,Bmal1,Brain and muscle ARNT-like 1,Class E basic helix-loop-helix protein 5 (bHLHe5),JAP3,MOP3,Member of PAS protein 3,PAS domain-containing protein 3,PASD3,TIC,bHLH-PAS protein JAP3,bHLHe5,bmal1b'

Target products collectionGo to BMAL1/ARNTL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1499-Ag-1/ GM-Tg-hg-SE1499-Ag-2 Human BMAL1/ARNTL protein Human
GM-Tg-rg-SE1499-Ag-1/ GM-Tg-rg-SE1499-Ag-2 Rat BMAL1/ARNTL protein Rat
GM-Tg-mg-SE1499-Ag-1/ GM-Tg-mg-SE1499-Ag-2 Mouse BMAL1/ARNTL protein Mouse
GM-Tg-cynog-SE1499-Ag-1/ GM-Tg-cynog-SE1499-Ag-2 Cynomolgus/Rhesus macaque BMAL1/ARNTL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1499-Ag-1/ GM-Tg-felg-SE1499-Ag-2 Feline BMAL1/ARNTL protein Feline
GM-Tg-cang-SE1499-Ag-1/ GM-Tg-cang-SE1499-Ag-2 Canine BMAL1/ARNTL protein Canine
GM-Tg-bovg-SE1499-Ag-1/ GM-Tg-bovg-SE1499-Ag-2 Bovine BMAL1/ARNTL protein Bovine
GM-Tg-equg-SE1499-Ag-1/ GM-Tg-equg-SE1499-Ag-2 Equine BMAL1/ARNTL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1499-Ag-1/ GM-Tg-hg-SE1499-Ag-2; GM-Tg-rg-SE1499-Ag-1/ GM-Tg-rg-SE1499-Ag-2;
GM-Tg-mg-SE1499-Ag-1/ GM-Tg-mg-SE1499-Ag-2; GM-Tg-cynog-SE1499-Ag-1/ GM-Tg-cynog-SE1499-Ag-2;
GM-Tg-felg-SE1499-Ag-1/ GM-Tg-felg-SE1499-Ag-2; GM-Tg-cang-SE1499-Ag-1/ GM-Tg-cang-SE1499-Ag-2;
GM-Tg-bovg-SE1499-Ag-1/ GM-Tg-bovg-SE1499-Ag-2; GM-Tg-equg-SE1499-Ag-1/ GM-Tg-equg-SE1499-Ag-2
Products Name BMAL1/ARNTL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BMAL1/ARNTL
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BMAL1/ARNTL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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