Explore BMAL1/ARNTL gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021]
| Target ID |
GM-SE1499
|
| Target Name |
BMAL1/ARNTL
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
406
|
| Gene ID |
100034115 (Equus caballus), 101091727 (Felis catus), 11865 (Mus musculus), 29657 (Rattus norvegicus)
406 (Homo sapiens), 476860 (Canis lupus familiaris), 530705 (Bos taurus), 700464 (Macaca mulatta)
|
| Target Alternative Names |
ARNTL,ARNTL1,Arnt3,Arntl,Aryl hydrocarbon receptor nuclear translocator-like protein 1,BMAL1,BMAL1b,BMAL1c,Basic helix-loop-helix ARNT-like protein 1,Basic-helix-loop-helix-PAS protein MOP3,Bmal1,Brain and muscle ARNT-like 1,Class E basic helix-loop-helix protein 5 (bHLHe5),JAP3,MOP3,Member of PAS protein 3,PAS domain-containing protein 3,PASD3,TIC,bHLH-PAS protein JAP3,bHLHe5,bmal1b'
|
| Uniprot Accession |
A0MLS5,Q9WTL8,Q9EPW1,O00327
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000012118, ENSMUSG00000055116, ENSG00000133794, ENSCAFG00845020372, ENSBTAG00000013029, ENSMMUG00000009690
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BMAL1/ARNTL cDNA Clones/ORF Plasmid
BMAL1/ARNTL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo406 | Pre-made Human BMAL1/TIC/JAP3 siRNA oligo Duplex | 406 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29657 | Pre-made Rat Bmal1/Arntl siRNA oligo Duplex | 29657 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11865 | Pre-made Mouse Bmal1/MOP3/Arnt3 siRNA oligo Duplex | 11865 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700464 | Pre-made Cynomolgus/Rhesus macaque ARNTL siRNA oligo Duplex | 700464 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091727 | Pre-made Cat/Feline ARNTL siRNA oligo Duplex | 101091727 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476860 | Pre-made Dog/Canine ARNTL/BMAL1 siRNA oligo Duplex | 476860 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530705 | Pre-made Bovines/Cattle ARNTL siRNA oligo Duplex | 530705 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034115 | Pre-made Equine/Horse ARNTL/BMAL1 siRNA oligo Duplex | 100034115 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMAL1/ARNTL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1499-Ab | Human | Anti-Human BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1499-Ab | Rat | Anti-Rat BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1499-Ab | Mouse | Anti-Mouse BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1499-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1499-Ab | Cat/Feline | Anti-Cat/Feline BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1499-Ab | Dog/Canine | Anti-Dog/Canine BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1499-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1499-Ab | Equine/Horse | Anti-Equine/Horse BMAL1/ARNTL monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
BMAL1/ARNTL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1499-Ag | Human | Human BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1499-Ag | Rat | Rat BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1499-Ag | Mouse | Mouse BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1499-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1499-Ag | Cat/Feline | Cat/Feline BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1499-Ag | Dog/Canine | Dog/Canine BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1499-Ag | Bovines/Cattle | Bovines/Cattle BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1499-Ag | Equine/Horse | Equine/Horse BMAL1/ARNTL recombinant protein | Mammalian cell | Detail |
