Recombinant multi-species GLIS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GLIS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4833409N03Rik,E330013K21Rik,GLI-similar 3,GLIS3,Glis3,NDH,RGD1565505,ZNF515,Zinc finger protein 515,Zinc finger protein GLIS3

Target products collectionGo to GLIS3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1453-Ag-1/ GM-Tg-hg-SE1453-Ag-2 Human GLIS3 protein Human
GM-Tg-rg-SE1453-Ag-1/ GM-Tg-rg-SE1453-Ag-2 Rat GLIS3 protein Rat
GM-Tg-mg-SE1453-Ag-1/ GM-Tg-mg-SE1453-Ag-2 Mouse GLIS3 protein Mouse
GM-Tg-cynog-SE1453-Ag-1/ GM-Tg-cynog-SE1453-Ag-2 Cynomolgus/Rhesus macaque GLIS3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1453-Ag-1/ GM-Tg-felg-SE1453-Ag-2 Feline GLIS3 protein Feline
GM-Tg-cang-SE1453-Ag-1/ GM-Tg-cang-SE1453-Ag-2 Canine GLIS3 protein Canine
GM-Tg-bovg-SE1453-Ag-1/ GM-Tg-bovg-SE1453-Ag-2 Bovine GLIS3 protein Bovine
GM-Tg-equg-SE1453-Ag-1/ GM-Tg-equg-SE1453-Ag-2 Equine GLIS3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1453-Ag-1/ GM-Tg-hg-SE1453-Ag-2; GM-Tg-rg-SE1453-Ag-1/ GM-Tg-rg-SE1453-Ag-2;
GM-Tg-mg-SE1453-Ag-1/ GM-Tg-mg-SE1453-Ag-2; GM-Tg-cynog-SE1453-Ag-1/ GM-Tg-cynog-SE1453-Ag-2;
GM-Tg-felg-SE1453-Ag-1/ GM-Tg-felg-SE1453-Ag-2; GM-Tg-cang-SE1453-Ag-1/ GM-Tg-cang-SE1453-Ag-2;
GM-Tg-bovg-SE1453-Ag-1/ GM-Tg-bovg-SE1453-Ag-2; GM-Tg-equg-SE1453-Ag-1/ GM-Tg-equg-SE1453-Ag-2
Products Name GLIS3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GLIS3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GLIS3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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