Explore GLIS3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE1453
|
| Target Name |
GLIS3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
169792
|
| Gene ID |
100051202 (Equus caballus), 101100094 (Felis catus), 169792 (Homo sapiens), 226075 (Mus musculus) 484179 (Canis lupus familiaris), 524909 (Bos taurus), 680671 (Rattus norvegicus), 694900 (Macaca mulatta)
|
| Target Alternative Names |
4833409N03Rik,E330013K21Rik,GLI-similar 3,GLIS3,Glis3,NDH,RGD1565505,ZNF515,Zinc finger protein 515,Zinc finger protein GLIS3
|
| Uniprot Accession |
Q8NEA6,Q6XP49
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSECAG00000020544, ENSG00000107249, ENSMUSG00000052942, ENSCAFG00845002759, ENSBTAG00000052736, ENSMMUG00000057568
|
GLIS3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo169792 | Pre-made Human GLIS3/NDH/ZNF515 siRNA oligo Duplex | 169792 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo680671 | Pre-made Rat Glis3/RGD1565505 siRNA oligo Duplex | 680671 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo226075 | Pre-made Mouse Glis3/4833409N03Rik/E330013K21Rik siRNA oligo Duplex | 226075 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694900 | Pre-made Cynomolgus/Rhesus macaque GLIS3 siRNA oligo Duplex | 694900 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100094 | Pre-made Cat/Feline GLIS3 siRNA oligo Duplex | 101100094 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484179 | Pre-made Dog/Canine GLIS3 siRNA oligo Duplex | 484179 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524909 | Pre-made Bovines/Cattle GLIS3 siRNA oligo Duplex | 524909 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051202 | Pre-made Equine/Horse GLIS3 siRNA oligo Duplex | 100051202 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GLIS3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1453-Ab | Human | Anti-Human GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1453-Ab | Rat | Anti-Rat GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1453-Ab | Mouse | Anti-Mouse GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1453-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1453-Ab | Cat/Feline | Anti-Cat/Feline GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1453-Ab | Dog/Canine | Anti-Dog/Canine GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1453-Ab | Bovines/Cattle | Anti-Bovines/Cattle GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1453-Ab | Equine/Horse | Anti-Equine/Horse GLIS3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GLIS3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1453-Ag | Human | Human GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1453-Ag | Rat | Rat GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1453-Ag | Mouse | Mouse GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1453-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1453-Ag | Cat/Feline | Cat/Feline GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1453-Ag | Dog/Canine | Dog/Canine GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1453-Ag | Bovines/Cattle | Bovines/Cattle GLIS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1453-Ag | Equine/Horse | Equine/Horse GLIS3 recombinant protein | Mammalian cell | Detail |