Recombinant multi-species TSH Beta/TSHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TSH Beta/TSHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
The Alternative Names of target: TSH Beta,TSH-B,TSH-BETA,TSH-beta),TSHB,Thyroid-stimulating hormone subunit beta (TSH-B,Thyrotropin beta chain,Thyrotropin subunit beta,Tshb
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1348-Ag-1/ GM-Tg-hg-SE1348-Ag-2 | Human TSH Beta/TSHB protein | Human |
| GM-Tg-rg-SE1348-Ag-1/ GM-Tg-rg-SE1348-Ag-2 | Rat TSH Beta/TSHB protein | Rat |
| GM-Tg-mg-SE1348-Ag-1/ GM-Tg-mg-SE1348-Ag-2 | Mouse TSH Beta/TSHB protein | Mouse |
| GM-Tg-cynog-SE1348-Ag-1/ GM-Tg-cynog-SE1348-Ag-2 | Cynomolgus/Rhesus macaque TSH Beta/TSHB protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1348-Ag-1/ GM-Tg-felg-SE1348-Ag-2 | Feline TSH Beta/TSHB protein | Feline |
| GM-Tg-cang-SE1348-Ag-1/ GM-Tg-cang-SE1348-Ag-2 | Canine TSH Beta/TSHB protein | Canine |
| GM-Tg-bovg-SE1348-Ag-1/ GM-Tg-bovg-SE1348-Ag-2 | Bovine TSH Beta/TSHB protein | Bovine |
| GM-Tg-equg-SE1348-Ag-1/ GM-Tg-equg-SE1348-Ag-2 | Equine TSH Beta/TSHB protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1348-Ag-1/ GM-Tg-hg-SE1348-Ag-2;
GM-Tg-rg-SE1348-Ag-1/ GM-Tg-rg-SE1348-Ag-2;
GM-Tg-mg-SE1348-Ag-1/ GM-Tg-mg-SE1348-Ag-2; GM-Tg-cynog-SE1348-Ag-1/ GM-Tg-cynog-SE1348-Ag-2; GM-Tg-felg-SE1348-Ag-1/ GM-Tg-felg-SE1348-Ag-2; GM-Tg-cang-SE1348-Ag-1/ GM-Tg-cang-SE1348-Ag-2; GM-Tg-bovg-SE1348-Ag-1/ GM-Tg-bovg-SE1348-Ag-2; GM-Tg-equg-SE1348-Ag-1/ GM-Tg-equg-SE1348-Ag-2 |
| Products Name | TSH Beta/TSHB protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | TSH Beta/TSHB |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TSH Beta/TSHB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.