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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
| Target ID |
GM-SE1348
|
| Target Name |
TSH Beta/TSHB
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7252
|
| Gene ID |
100034188 (Equus caballus), 22094 (Mus musculus), 25653 (Rattus norvegicus), 281552 (Bos taurus) 403973 (Canis lupus familiaris), 554350 (Felis catus), 709374 (Macaca mulatta), 7252 (Homo sapiens)
|
| Target Alternative Names |
TSH Beta,TSH-B,TSH-BETA,TSH-beta),TSHB,Thyroid-stimulating hormone subunit beta (TSH-B,Thyrotropin beta chain,Thyrotropin subunit beta,Tshb
|
| Uniprot Accession |
Q28376,P12656,P04652,P01223,P54828,Q52R90,P01222
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Diagnostics Biomarker
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Thyroid hormone synthesis, Regulation of lipolysis in adipocytes, Autoimmune thyroid disease
|
| Gene Ensembl |
ENSMUSG00000027857, ENSBTAG00000006295, ENSCAFG00845027709, ENSG00000134200
|
Pre-made viral vector of TSH Beta/TSHB cDNA Clones/ORF Plasmid
TSH Beta/TSHB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7252 | Pre-made Human TSHB/TSH-B/TSH-BETA siRNA oligo Duplex | 7252 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25653 | Pre-made Rat Tshb siRNA oligo Duplex | 25653 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22094 | Pre-made Mouse Tshb siRNA oligo Duplex | 22094 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709374 | Pre-made Cynomolgus/Rhesus macaque TSHB siRNA oligo Duplex | 709374 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo554350 | Pre-made Cat/Feline TSHB siRNA oligo Duplex | 554350 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403973 | Pre-made Dog/Canine TSHB siRNA oligo Duplex | 403973 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281552 | Pre-made Bovines/Cattle TSHB siRNA oligo Duplex | 281552 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034188 | Pre-made Equine/Horse TSHB/TSH-BETA siRNA oligo Duplex | 100034188 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TSH Beta/TSHB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1348-Ab | Human | Anti-Human TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-SE1348-Ab | Rat | Anti-Rat TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-SE1348-Ab | Mouse | Anti-Mouse TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-SE1348-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-SE1348-Ab | Cat/Feline | Anti-Cat/Feline TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-SE1348-Ab | Dog/Canine | Anti-Dog/Canine TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-SE1348-Ab | Bovines/Cattle | Anti-Bovines/Cattle TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-SE1348-Ab | Equine/Horse | Anti-Equine/Horse TSH Beta/TSHB monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
TSH Beta/TSHB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1348-Ag | Human | Human TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1348-Ag | Rat | Rat TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1348-Ag | Mouse | Mouse TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1348-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1348-Ag | Cat/Feline | Cat/Feline TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1348-Ag | Dog/Canine | Dog/Canine TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1348-Ag | Bovines/Cattle | Bovines/Cattle TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1348-Ag | Equine/Horse | Equine/Horse TSH Beta/TSHB recombinant protein | Mammalian cell | Detail |