Recombinant multi-species RLN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RLN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]
The Alternative Names of target: H2,H2-RLX,Prorelaxin H2,RLN,RLN1,RLN2,RLXH2,bA12D24.1.1,bA12D24.1.2,relaxin

Target products collectionGo to RLN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1242-Ag-1/ GM-Tg-hg-SE1242-Ag-2 Human RLN2 protein Human
GM-Tg-rg-SE1242-Ag-1/ GM-Tg-rg-SE1242-Ag-2 Rat RLN2 protein Rat
GM-Tg-mg-SE1242-Ag-1/ GM-Tg-mg-SE1242-Ag-2 Mouse RLN2 protein Mouse
GM-Tg-cynog-SE1242-Ag-1/ GM-Tg-cynog-SE1242-Ag-2 Cynomolgus/Rhesus macaque RLN2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1242-Ag-1/ GM-Tg-felg-SE1242-Ag-2 Feline RLN2 protein Feline
GM-Tg-cang-SE1242-Ag-1/ GM-Tg-cang-SE1242-Ag-2 Canine RLN2 protein Canine
GM-Tg-bovg-SE1242-Ag-1/ GM-Tg-bovg-SE1242-Ag-2 Bovine RLN2 protein Bovine
GM-Tg-equg-SE1242-Ag-1/ GM-Tg-equg-SE1242-Ag-2 Equine RLN2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1242-Ag-1/ GM-Tg-hg-SE1242-Ag-2; GM-Tg-rg-SE1242-Ag-1/ GM-Tg-rg-SE1242-Ag-2;
GM-Tg-mg-SE1242-Ag-1/ GM-Tg-mg-SE1242-Ag-2; GM-Tg-cynog-SE1242-Ag-1/ GM-Tg-cynog-SE1242-Ag-2;
GM-Tg-felg-SE1242-Ag-1/ GM-Tg-felg-SE1242-Ag-2; GM-Tg-cang-SE1242-Ag-1/ GM-Tg-cang-SE1242-Ag-2;
GM-Tg-bovg-SE1242-Ag-1/ GM-Tg-bovg-SE1242-Ag-2; GM-Tg-equg-SE1242-Ag-1/ GM-Tg-equg-SE1242-Ag-2
Products Name RLN2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RLN2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RLN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.