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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]
| Target ID |
GM-SE1242
|
| Target Name |
RLN2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6019
|
| Gene ID |
403742 (Canis lupus familiaris), 6019 (Homo sapiens)
|
| Target Alternative Names |
H2,H2-RLX,Prorelaxin H2,RLN,RLN1,RLN2,RLXH2,bA12D24.1.1,bA12D24.1.2,relaxin
|
| Uniprot Accession |
Q9TRM8,P04090
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Relaxin signaling pathway
|
| Gene Ensembl |
ENSG00000107014
|
RLN2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6019 | Pre-made Human RLN2/H2/RLXH2 siRNA oligo Duplex | 6019 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403742 | Pre-made Dog/Canine RLN2/RLN/RLN1 siRNA oligo Duplex | 403742 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
RLN2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1242-Ab | Human | Anti-Human RLN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1242-Ab | Dog/Canine | Anti-Dog/Canine RLN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
RLN2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1242-Ag | Human | Human RLN2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1242-Ag | Dog/Canine | Dog/Canine RLN2 recombinant protein | Mammalian cell | Detail |