Recombinant multi-species PRSS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRSS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]
The Alternative Names of target: Anionic trypsinogen,PRSS2,Serine protease 2,TRY2,TRY8,TRYP2,TRYP8,Trypsin II,Trypsin-2,try10

Target products collectionGo to PRSS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1211-Ag-1/ GM-Tg-hg-SE1211-Ag-2 Human PRSS2 protein Human
GM-Tg-rg-SE1211-Ag-1/ GM-Tg-rg-SE1211-Ag-2 Rat PRSS2 protein Rat
GM-Tg-mg-SE1211-Ag-1/ GM-Tg-mg-SE1211-Ag-2 Mouse PRSS2 protein Mouse
GM-Tg-cynog-SE1211-Ag-1/ GM-Tg-cynog-SE1211-Ag-2 Cynomolgus/Rhesus macaque PRSS2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1211-Ag-1/ GM-Tg-felg-SE1211-Ag-2 Feline PRSS2 protein Feline
GM-Tg-cang-SE1211-Ag-1/ GM-Tg-cang-SE1211-Ag-2 Canine PRSS2 protein Canine
GM-Tg-bovg-SE1211-Ag-1/ GM-Tg-bovg-SE1211-Ag-2 Bovine PRSS2 protein Bovine
GM-Tg-equg-SE1211-Ag-1/ GM-Tg-equg-SE1211-Ag-2 Equine PRSS2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1211-Ag-1/ GM-Tg-hg-SE1211-Ag-2; GM-Tg-rg-SE1211-Ag-1/ GM-Tg-rg-SE1211-Ag-2;
GM-Tg-mg-SE1211-Ag-1/ GM-Tg-mg-SE1211-Ag-2; GM-Tg-cynog-SE1211-Ag-1/ GM-Tg-cynog-SE1211-Ag-2;
GM-Tg-felg-SE1211-Ag-1/ GM-Tg-felg-SE1211-Ag-2; GM-Tg-cang-SE1211-Ag-1/ GM-Tg-cang-SE1211-Ag-2;
GM-Tg-bovg-SE1211-Ag-1/ GM-Tg-bovg-SE1211-Ag-2; GM-Tg-equg-SE1211-Ag-1/ GM-Tg-equg-SE1211-Ag-2
Products Name PRSS2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRSS2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRSS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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