Recombinant multi-species NBL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NBL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
The Alternative Names of target: NBL1,Neuroblastoma suppressor of tumorigenicity 1,DAN domain family member 1, Protein N03, Zinc finger protein DAN,NB,DAN,NO3,DAND1,D1S1733E

Target products collectionGo to NBL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1121-Ab-1/ GM-Tg-hg-SE1121-Ab-2 Human NBL1 protein Human
GM-Tg-rg-SE1121-Ab-1/ GM-Tg-rg-SE1121-Ab-2 Rat NBL1 protein Rat
GM-Tg-mg-SE1121-Ab-1/ GM-Tg-mg-SE1121-Ab-2 Mouse NBL1 protein Mouse
GM-Tg-cynog-SE1121-Ab-1/ GM-Tg-cynog-SE1121-Ab-2 Cynomolgus/Rhesus macaque NBL1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1121-Ab-1/ GM-Tg-felg-SE1121-Ab-2 Feline NBL1 protein Feline
GM-Tg-cang-SE1121-Ab-1/ GM-Tg-cang-SE1121-Ab-2 Canine NBL1 protein Canine
GM-Tg-bovg-SE1121-Ab-1/ GM-Tg-bovg-SE1121-Ab-2 Bovine NBL1 protein Bovine
GM-Tg-equg-SE1121-Ab-1/ GM-Tg-equg-SE1121-Ab-2 Equine NBL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1121-Ab-1/ GM-Tg-hg-SE1121-Ab-2; GM-Tg-rg-SE1121-Ab-1/ GM-Tg-rg-SE1121-Ab-2;
GM-Tg-mg-SE1121-Ab-1/ GM-Tg-mg-SE1121-Ab-2; GM-Tg-cynog-SE1121-Ab-1/ GM-Tg-cynog-SE1121-Ab-2;
GM-Tg-felg-SE1121-Ab-1/ GM-Tg-felg-SE1121-Ab-2; GM-Tg-cang-SE1121-Ab-1/ GM-Tg-cang-SE1121-Ab-2;
GM-Tg-bovg-SE1121-Ab-1/ GM-Tg-bovg-SE1121-Ab-2; GM-Tg-equg-SE1121-Ab-1/ GM-Tg-equg-SE1121-Ab-2
Products Name NBL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NBL1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NBL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.