Explore NBL1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
| Target ID |
GM-SE1121
|
| Target Name |
NBL1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4681
|
| Gene ID |
100071893 (Equus caballus), 101090533 (Felis catus), 17965 (Mus musculus), 4681 (Homo sapiens)
487403 (Canis lupus familiaris), 50594 (Rattus norvegicus), 535280 (Bos taurus), 703641 (Macaca mulatta)
|
| Target Alternative Names |
NBL1,Nbl1,DAN,NO3,Dana,D4H1S1733E,NB,DAND1,D1S1733E
|
| Uniprot Accession |
Q61477,P41271,Q06880
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000007317, ENSMUSG00000041120, ENSG00000158747, ENSCAFG00845003226, ENSBTAG00000005140, ENSMMUG00000032231
|
| Target Classification |
Tumor-associated antigen (TAA)
|
NBL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4681 | Pre-made Human NBL1/NB/DAN siRNA oligo Duplex | 4681 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50594 | Pre-made Rat Nbl1 siRNA oligo Duplex | 50594 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17965 | Pre-made Mouse Nbl1/DAN/NO3 siRNA oligo Duplex | 17965 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703641 | Pre-made Cynomolgus/Rhesus macaque NBL1 siRNA oligo Duplex | 703641 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090533 | Pre-made Cat/Feline NBL1 siRNA oligo Duplex | 101090533 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487403 | Pre-made Dog/Canine NBL1 siRNA oligo Duplex | 487403 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535280 | Pre-made Bovines/Cattle NBL1 siRNA oligo Duplex | 535280 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071893 | Pre-made Equine/Horse NBL1 siRNA oligo Duplex | 100071893 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NBL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1121-Ab | Human | Anti-Human NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1121-Ab | Rat | Anti-Rat NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1121-Ab | Mouse | Anti-Mouse NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1121-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1121-Ab | Cat/Feline | Anti-Cat/Feline NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1121-Ab | Dog/Canine | Anti-Dog/Canine NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1121-Ab | Bovines/Cattle | Anti-Bovines/Cattle NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1121-Ab | Equine/Horse | Anti-Equine/Horse NBL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NBL1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1121-Ag | Human | Human NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1121-Ag | Rat | Rat NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1121-Ag | Mouse | Mouse NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1121-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1121-Ag | Cat/Feline | Cat/Feline NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1121-Ag | Dog/Canine | Dog/Canine NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1121-Ag | Bovines/Cattle | Bovines/Cattle NBL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1121-Ag | Equine/Horse | Equine/Horse NBL1 recombinant protein | Mammalian cell | Detail |
