Recombinant multi-species LOXL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LOXL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016]
The Alternative Names of target: LOL,LOXL,LOXL1,Loxl,Loxl1,Lysyl oxidase homolog 1,Lysyl oxidase-like protein 1 (LOL)

Target products collectionGo to LOXL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1077-Ag-1/ GM-Tg-hg-SE1077-Ag-2 Human LOXL1 protein Human
GM-Tg-rg-SE1077-Ag-1/ GM-Tg-rg-SE1077-Ag-2 Rat LOXL1 protein Rat
GM-Tg-mg-SE1077-Ag-1/ GM-Tg-mg-SE1077-Ag-2 Mouse LOXL1 protein Mouse
GM-Tg-cynog-SE1077-Ag-1/ GM-Tg-cynog-SE1077-Ag-2 Cynomolgus/Rhesus macaque LOXL1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1077-Ag-1/ GM-Tg-felg-SE1077-Ag-2 Feline LOXL1 protein Feline
GM-Tg-cang-SE1077-Ag-1/ GM-Tg-cang-SE1077-Ag-2 Canine LOXL1 protein Canine
GM-Tg-bovg-SE1077-Ag-1/ GM-Tg-bovg-SE1077-Ag-2 Bovine LOXL1 protein Bovine
GM-Tg-equg-SE1077-Ag-1/ GM-Tg-equg-SE1077-Ag-2 Equine LOXL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1077-Ag-1/ GM-Tg-hg-SE1077-Ag-2; GM-Tg-rg-SE1077-Ag-1/ GM-Tg-rg-SE1077-Ag-2;
GM-Tg-mg-SE1077-Ag-1/ GM-Tg-mg-SE1077-Ag-2; GM-Tg-cynog-SE1077-Ag-1/ GM-Tg-cynog-SE1077-Ag-2;
GM-Tg-felg-SE1077-Ag-1/ GM-Tg-felg-SE1077-Ag-2; GM-Tg-cang-SE1077-Ag-1/ GM-Tg-cang-SE1077-Ag-2;
GM-Tg-bovg-SE1077-Ag-1/ GM-Tg-bovg-SE1077-Ag-2; GM-Tg-equg-SE1077-Ag-1/ GM-Tg-equg-SE1077-Ag-2
Products Name LOXL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LOXL1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LOXL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.