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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016]
| Target ID |
GM-SE1077
|
| Target Name |
LOXL1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4016
|
| Gene ID |
100051862 (Equus caballus), 100686150 (Canis lupus familiaris), 101089616 (Felis catus), 16949 (Mus musculus) 281903 (Bos taurus), 315714 (Rattus norvegicus), 4016 (Homo sapiens), 706464 (Macaca mulatta)
|
| Target Alternative Names |
LOL,LOXL,LOXL1,Loxl,Loxl1,Lysyl oxidase homolog 1,Lysyl oxidase-like protein 1 (LOL)
|
| Uniprot Accession |
P97873,Q95L39,Q08397
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSECAG00000023405, ENSCAFG00845028254, ENSMUSG00000032334, ENSBTAG00000009086, ENSG00000129038, ENSMMUG00000003638
|
Pre-made viral vector of LOXL1 cDNA Clones/ORF Plasmid
LOXL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4016 | Pre-made Human LOXL1/LOL/LOXL siRNA oligo Duplex | 4016 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo315714 | Pre-made Rat Loxl1 siRNA oligo Duplex | 315714 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16949 | Pre-made Mouse Loxl1/Loxl siRNA oligo Duplex | 16949 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706464 | Pre-made Cynomolgus/Rhesus macaque LOXL1 siRNA oligo Duplex | 706464 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089616 | Pre-made Cat/Feline LOXL1 siRNA oligo Duplex | 101089616 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100686150 | Pre-made Dog/Canine LOXL1 siRNA oligo Duplex | 100686150 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281903 | Pre-made Bovines/Cattle LOXL1 siRNA oligo Duplex | 281903 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051862 | Pre-made Equine/Horse LOXL1 siRNA oligo Duplex | 100051862 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LOXL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1077-Ab | Human | Anti-Human LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1077-Ab | Rat | Anti-Rat LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1077-Ab | Mouse | Anti-Mouse LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1077-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1077-Ab | Cat/Feline | Anti-Cat/Feline LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1077-Ab | Dog/Canine | Anti-Dog/Canine LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1077-Ab | Bovines/Cattle | Anti-Bovines/Cattle LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1077-Ab | Equine/Horse | Anti-Equine/Horse LOXL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LOXL1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1077-Ag | Human | Human LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1077-Ag | Rat | Rat LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1077-Ag | Mouse | Mouse LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1077-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1077-Ag | Cat/Feline | Cat/Feline LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1077-Ag | Dog/Canine | Dog/Canine LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1077-Ag | Bovines/Cattle | Bovines/Cattle LOXL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1077-Ag | Equine/Horse | Equine/Horse LOXL1 recombinant protein | Mammalian cell | Detail |