Recombinant multi-species LHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CGB4,Gm29035,HH23,LH,LH-B,LHB,LSH-B,LSH-beta,LSH-beta),Lhb,Luteinizing hormone subunit beta (LH-B,Lutropin beta chain,Lutropin subunit beta
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1072-Ag-1/ GM-Tg-hg-SE1072-Ag-2 | Human LHB protein | Human |
| GM-Tg-rg-SE1072-Ag-1/ GM-Tg-rg-SE1072-Ag-2 | Rat LHB protein | Rat |
| GM-Tg-mg-SE1072-Ag-1/ GM-Tg-mg-SE1072-Ag-2 | Mouse LHB protein | Mouse |
| GM-Tg-cynog-SE1072-Ag-1/ GM-Tg-cynog-SE1072-Ag-2 | Cynomolgus/Rhesus macaque LHB protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1072-Ag-1/ GM-Tg-felg-SE1072-Ag-2 | Feline LHB protein | Feline |
| GM-Tg-cang-SE1072-Ag-1/ GM-Tg-cang-SE1072-Ag-2 | Canine LHB protein | Canine |
| GM-Tg-bovg-SE1072-Ag-1/ GM-Tg-bovg-SE1072-Ag-2 | Bovine LHB protein | Bovine |
| GM-Tg-equg-SE1072-Ag-1/ GM-Tg-equg-SE1072-Ag-2 | Equine LHB protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1072-Ag-1/ GM-Tg-hg-SE1072-Ag-2;
GM-Tg-rg-SE1072-Ag-1/ GM-Tg-rg-SE1072-Ag-2;
GM-Tg-mg-SE1072-Ag-1/ GM-Tg-mg-SE1072-Ag-2; GM-Tg-cynog-SE1072-Ag-1/ GM-Tg-cynog-SE1072-Ag-2; GM-Tg-felg-SE1072-Ag-1/ GM-Tg-felg-SE1072-Ag-2; GM-Tg-cang-SE1072-Ag-1/ GM-Tg-cang-SE1072-Ag-2; GM-Tg-bovg-SE1072-Ag-1/ GM-Tg-bovg-SE1072-Ag-2; GM-Tg-equg-SE1072-Ag-1/ GM-Tg-equg-SE1072-Ag-2 |
| Products Name | LHB protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LHB |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LHB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.