Explore LHB gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE1072
|
| Target Name |
LHB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3972
|
| Gene ID |
100429401 (Macaca mulatta), 16866 (Mus musculus), 25329 (Rattus norvegicus), 280839 (Bos taurus)
3972 (Homo sapiens), 403959 (Canis lupus familiaris)
|
| Target Alternative Names |
CGB4,Gm29035,HH23,LH,LH-B,LHB,LSH-B,LSH-beta,LSH-beta),Lhb,Luteinizing hormone subunit beta (LH-B,Lutropin beta chain,Lutropin subunit beta
|
| Uniprot Accession |
O09108,P01230,P04651,P01229,P18842
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Ovary Cancer, breast cancer
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, GnRH signaling pathway, Ovarian steroidogenesis, Prolactin signaling pathway, GnRH secretion
|
| Gene Ensembl |
ENSMMUG00000015793, ENSMUSG00000100916, ENSBTAG00000038735, ENSG00000104826
|
Pre-made viral vector of LHB cDNA Clones/ORF Plasmid
LHB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3972 | Pre-made Human LHB/CGB4/HH23 siRNA oligo Duplex | 3972 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25329 | Pre-made Rat Lhb siRNA oligo Duplex | 25329 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16866 | Pre-made Mouse Lhb/LH/LH-B siRNA oligo Duplex | 16866 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100429401 | Pre-made Cynomolgus/Rhesus macaque LHB siRNA oligo Duplex | 100429401 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403959 | Pre-made Dog/Canine LHB/LH/LH-B siRNA oligo Duplex | 403959 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280839 | Pre-made Bovines/Cattle LHB siRNA oligo Duplex | 280839 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
LHB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1072-Ab | Human | Anti-Human LHB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1072-Ab | Rat | Anti-Rat LHB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1072-Ab | Mouse | Anti-Mouse LHB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1072-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LHB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1072-Ab | Dog/Canine | Anti-Dog/Canine LHB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1072-Ab | Bovines/Cattle | Anti-Bovines/Cattle LHB monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LHB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1072-Ag | Human | Human LHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1072-Ag | Rat | Rat LHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1072-Ag | Mouse | Mouse LHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1072-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1072-Ag | Dog/Canine | Dog/Canine LHB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1072-Ag | Bovines/Cattle | Bovines/Cattle LHB recombinant protein | Mammalian cell | Detail |
