Recombinant multi-species HYAL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HYAL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Fus2,HYAL-1,HYAL1,Hya1,Hyal-1,Hyal1,Hyaluronidase-1,Hyaluronoglucosaminidase-1,LUCA1,Lung carcinoma protein 1 (LuCa-1),MPS9,NAT6,Nat6

Target products collectionGo to HYAL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0973-Ag-1/ GM-Tg-hg-SE0973-Ag-2 Human HYAL1 protein Human
GM-Tg-rg-SE0973-Ag-1/ GM-Tg-rg-SE0973-Ag-2 Rat HYAL1 protein Rat
GM-Tg-mg-SE0973-Ag-1/ GM-Tg-mg-SE0973-Ag-2 Mouse HYAL1 protein Mouse
GM-Tg-cynog-SE0973-Ag-1/ GM-Tg-cynog-SE0973-Ag-2 Cynomolgus/Rhesus macaque HYAL1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0973-Ag-1/ GM-Tg-felg-SE0973-Ag-2 Feline HYAL1 protein Feline
GM-Tg-cang-SE0973-Ag-1/ GM-Tg-cang-SE0973-Ag-2 Canine HYAL1 protein Canine
GM-Tg-bovg-SE0973-Ag-1/ GM-Tg-bovg-SE0973-Ag-2 Bovine HYAL1 protein Bovine
GM-Tg-equg-SE0973-Ag-1/ GM-Tg-equg-SE0973-Ag-2 Equine HYAL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0973-Ag-1/ GM-Tg-hg-SE0973-Ag-2; GM-Tg-rg-SE0973-Ag-1/ GM-Tg-rg-SE0973-Ag-2;
GM-Tg-mg-SE0973-Ag-1/ GM-Tg-mg-SE0973-Ag-2; GM-Tg-cynog-SE0973-Ag-1/ GM-Tg-cynog-SE0973-Ag-2;
GM-Tg-felg-SE0973-Ag-1/ GM-Tg-felg-SE0973-Ag-2; GM-Tg-cang-SE0973-Ag-1/ GM-Tg-cang-SE0973-Ag-2;
GM-Tg-bovg-SE0973-Ag-1/ GM-Tg-bovg-SE0973-Ag-2; GM-Tg-equg-SE0973-Ag-1/ GM-Tg-equg-SE0973-Ag-2
Products Name HYAL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HYAL1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HYAL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.