Explore HYAL1 gene products and cross-species
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0973
|
| Target Name |
HYAL1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3373
|
| Gene ID |
15586 (Mus musculus), 3373 (Homo sapiens), 367166 (Rattus norvegicus), 515397 (Bos taurus) 608602 (Canis lupus familiaris), 702850 (Macaca mulatta)
|
| Target Alternative Names |
Fus2,HYAL-1,HYAL1,Hya1,Hyal-1,Hyal1,Hyaluronidase-1,Hyaluronoglucosaminidase-1,LUCA1,Lung carcinoma protein 1 (LuCa-1),MPS9,NAT6,Nat6
|
| Uniprot Accession |
Q91ZJ9,Q12794,Q76HN1,Q5E985
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Glycosaminoglycan degradation
|
| Gene Ensembl |
ENSMUSG00000010051, ENSG00000114378, ENSCAFG00845021903, ENSMMUG00000020121
|
Pre-made viral vector of HYAL1 cDNA Clones/ORF Plasmid
HYAL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3373 | Pre-made Human HYAL1/MPS9/NAT6 siRNA oligo Duplex | 3373 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo367166 | Pre-made Rat Hyal1 siRNA oligo Duplex | 367166 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15586 | Pre-made Mouse Hyal1/Fus2/Hya1 siRNA oligo Duplex | 15586 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702850 | Pre-made Cynomolgus/Rhesus macaque HYAL1 siRNA oligo Duplex | 702850 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608602 | Pre-made Dog/Canine HYAL1 siRNA oligo Duplex | 608602 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515397 | Pre-made Bovines/Cattle HYAL1 siRNA oligo Duplex | 515397 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
HYAL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0973-Ab | Human | Anti-Human HYAL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0973-Ab | Rat | Anti-Rat HYAL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0973-Ab | Mouse | Anti-Mouse HYAL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0973-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HYAL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0973-Ab | Dog/Canine | Anti-Dog/Canine HYAL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0973-Ab | Bovines/Cattle | Anti-Bovines/Cattle HYAL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HYAL1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0973-Ag | Human | Human HYAL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0973-Ag | Rat | Rat HYAL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0973-Ag | Mouse | Mouse HYAL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0973-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HYAL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0973-Ag | Dog/Canine | Dog/Canine HYAL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0973-Ag | Bovines/Cattle | Bovines/Cattle HYAL1 recombinant protein | Mammalian cell | Detail |