Recombinant multi-species FGF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]
The Alternative Names of target: FGF-3,FGF3,FGF5C,Fgf-3,Fgf3,Fgf5c,Fibroblast growth factor 3,HBGF-3,Heparin-binding growth factor 3 (HBGF-3),INT2,Int-2,Int-P,Int2,Proto-oncogene Int-2

Target products collectionGo to FGF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0921-Ag-1/ GM-Tg-hg-SE0921-Ag-2 Human FGF3 protein Human
GM-Tg-rg-SE0921-Ag-1/ GM-Tg-rg-SE0921-Ag-2 Rat FGF3 protein Rat
GM-Tg-mg-SE0921-Ag-1/ GM-Tg-mg-SE0921-Ag-2 Mouse FGF3 protein Mouse
GM-Tg-cynog-SE0921-Ag-1/ GM-Tg-cynog-SE0921-Ag-2 Cynomolgus/Rhesus macaque FGF3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0921-Ag-1/ GM-Tg-felg-SE0921-Ag-2 Feline FGF3 protein Feline
GM-Tg-cang-SE0921-Ag-1/ GM-Tg-cang-SE0921-Ag-2 Canine FGF3 protein Canine
GM-Tg-bovg-SE0921-Ag-1/ GM-Tg-bovg-SE0921-Ag-2 Bovine FGF3 protein Bovine
GM-Tg-equg-SE0921-Ag-1/ GM-Tg-equg-SE0921-Ag-2 Equine FGF3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0921-Ag-1/ GM-Tg-hg-SE0921-Ag-2; GM-Tg-rg-SE0921-Ag-1/ GM-Tg-rg-SE0921-Ag-2;
GM-Tg-mg-SE0921-Ag-1/ GM-Tg-mg-SE0921-Ag-2; GM-Tg-cynog-SE0921-Ag-1/ GM-Tg-cynog-SE0921-Ag-2;
GM-Tg-felg-SE0921-Ag-1/ GM-Tg-felg-SE0921-Ag-2; GM-Tg-cang-SE0921-Ag-1/ GM-Tg-cang-SE0921-Ag-2;
GM-Tg-bovg-SE0921-Ag-1/ GM-Tg-bovg-SE0921-Ag-2; GM-Tg-equg-SE0921-Ag-1/ GM-Tg-equg-SE0921-Ag-2
Products Name FGF3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FGF3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.