Explore FGF3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0921
|
| Target Name |
FGF3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2248
|
| Gene ID |
100146649 (Equus caballus), 111556666 (Felis catus), 14174 (Mus musculus), 170633 (Rattus norvegicus)
2248 (Homo sapiens), 611707 (Canis lupus familiaris), 618481 (Bos taurus), 708918 (Macaca mulatta)
|
| Target Alternative Names |
FGF-3,FGF3,FGF5C,Fgf-3,Fgf3,Fgf5c,Fibroblast growth factor 3,HBGF-3,Heparin-binding growth factor 3 (HBGF-3),INT2,Int-2,Int-P,Int2,Proto-oncogene Int-2
|
| Uniprot Accession |
P05524,P11487
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Chemical carcinogenesis - receptor activation, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000031321, ENSMUSG00000031074, ENSG00000186895, ENSCAFG00845015080, ENSBTAG00000008623, ENSMMUG00000051149
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of FGF3 cDNA Clones/ORF Plasmid
FGF3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2248 | Pre-made Human FGF3/INT2/HBGF-3 siRNA oligo Duplex | 2248 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170633 | Pre-made Rat Fgf3/Int2/Fgf5c siRNA oligo Duplex | 170633 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14174 | Pre-made Mouse Fgf3/Fgf-3/Fgf5c siRNA oligo Duplex | 14174 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708918 | Pre-made Cynomolgus/Rhesus macaque FGF3 siRNA oligo Duplex | 708918 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111556666 | Pre-made Cat/Feline FGF3 siRNA oligo Duplex | 111556666 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611707 | Pre-made Dog/Canine FGF3 siRNA oligo Duplex | 611707 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo618481 | Pre-made Bovines/Cattle FGF3/FGF5C siRNA oligo Duplex | 618481 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146649 | Pre-made Equine/Horse FGF3 siRNA oligo Duplex | 100146649 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0921-Ab | Human | Anti-Human FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0921-Ab | Rat | Anti-Rat FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0921-Ab | Mouse | Anti-Mouse FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0921-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0921-Ab | Cat/Feline | Anti-Cat/Feline FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0921-Ab | Dog/Canine | Anti-Dog/Canine FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0921-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0921-Ab | Equine/Horse | Anti-Equine/Horse FGF3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
FGF3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0921-Ag | Human | Human FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0921-Ag | Rat | Rat FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0921-Ag | Mouse | Mouse FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0921-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0921-Ag | Cat/Feline | Cat/Feline FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0921-Ag | Dog/Canine | Dog/Canine FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0921-Ag | Bovines/Cattle | Bovines/Cattle FGF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0921-Ag | Equine/Horse | Equine/Horse FGF3 recombinant protein | Mammalian cell | Detail |
