Recombinant multi-species DSPP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DSPP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jan 2016]
The Alternative Names of target: DFNA39,DGI1,DMP3,DPP,DSP,DSPP,Dentin sialophosphoprotein,Dmp2,Dmp3,Dpp,Dsp,Dspp,RDSP2

Target products collectionGo to DSPP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0895-Ag-1/ GM-Tg-hg-SE0895-Ag-2 Human DSPP protein Human
GM-Tg-rg-SE0895-Ag-1/ GM-Tg-rg-SE0895-Ag-2 Rat DSPP protein Rat
GM-Tg-mg-SE0895-Ag-1/ GM-Tg-mg-SE0895-Ag-2 Mouse DSPP protein Mouse
GM-Tg-cynog-SE0895-Ag-1/ GM-Tg-cynog-SE0895-Ag-2 Cynomolgus/Rhesus macaque DSPP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0895-Ag-1/ GM-Tg-felg-SE0895-Ag-2 Feline DSPP protein Feline
GM-Tg-cang-SE0895-Ag-1/ GM-Tg-cang-SE0895-Ag-2 Canine DSPP protein Canine
GM-Tg-bovg-SE0895-Ag-1/ GM-Tg-bovg-SE0895-Ag-2 Bovine DSPP protein Bovine
GM-Tg-equg-SE0895-Ag-1/ GM-Tg-equg-SE0895-Ag-2 Equine DSPP protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0895-Ag-1/ GM-Tg-hg-SE0895-Ag-2; GM-Tg-rg-SE0895-Ag-1/ GM-Tg-rg-SE0895-Ag-2;
GM-Tg-mg-SE0895-Ag-1/ GM-Tg-mg-SE0895-Ag-2; GM-Tg-cynog-SE0895-Ag-1/ GM-Tg-cynog-SE0895-Ag-2;
GM-Tg-felg-SE0895-Ag-1/ GM-Tg-felg-SE0895-Ag-2; GM-Tg-cang-SE0895-Ag-1/ GM-Tg-cang-SE0895-Ag-2;
GM-Tg-bovg-SE0895-Ag-1/ GM-Tg-bovg-SE0895-Ag-2; GM-Tg-equg-SE0895-Ag-1/ GM-Tg-equg-SE0895-Ag-2
Products Name DSPP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DSPP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DSPP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.