Recombinant multi-species DSPP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DSPP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jan 2016]
The Alternative Names of target: DFNA39,DGI1,DMP3,DPP,DSP,DSPP,Dentin sialophosphoprotein,Dmp2,Dmp3,Dpp,Dsp,Dspp,RDSP2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0895-Ag-1/ GM-Tg-hg-SE0895-Ag-2 | Human DSPP protein | Human |
| GM-Tg-rg-SE0895-Ag-1/ GM-Tg-rg-SE0895-Ag-2 | Rat DSPP protein | Rat |
| GM-Tg-mg-SE0895-Ag-1/ GM-Tg-mg-SE0895-Ag-2 | Mouse DSPP protein | Mouse |
| GM-Tg-cynog-SE0895-Ag-1/ GM-Tg-cynog-SE0895-Ag-2 | Cynomolgus/Rhesus macaque DSPP protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0895-Ag-1/ GM-Tg-felg-SE0895-Ag-2 | Feline DSPP protein | Feline |
| GM-Tg-cang-SE0895-Ag-1/ GM-Tg-cang-SE0895-Ag-2 | Canine DSPP protein | Canine |
| GM-Tg-bovg-SE0895-Ag-1/ GM-Tg-bovg-SE0895-Ag-2 | Bovine DSPP protein | Bovine |
| GM-Tg-equg-SE0895-Ag-1/ GM-Tg-equg-SE0895-Ag-2 | Equine DSPP protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0895-Ag-1/ GM-Tg-hg-SE0895-Ag-2;
GM-Tg-rg-SE0895-Ag-1/ GM-Tg-rg-SE0895-Ag-2;
GM-Tg-mg-SE0895-Ag-1/ GM-Tg-mg-SE0895-Ag-2; GM-Tg-cynog-SE0895-Ag-1/ GM-Tg-cynog-SE0895-Ag-2; GM-Tg-felg-SE0895-Ag-1/ GM-Tg-felg-SE0895-Ag-2; GM-Tg-cang-SE0895-Ag-1/ GM-Tg-cang-SE0895-Ag-2; GM-Tg-bovg-SE0895-Ag-1/ GM-Tg-bovg-SE0895-Ag-2; GM-Tg-equg-SE0895-Ag-1/ GM-Tg-equg-SE0895-Ag-2 |
| Products Name | DSPP protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DSPP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DSPP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.