Explore DSPP gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jan 2016]
| Target ID |
GM-SE0895
|
| Target Name |
DSPP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1834
|
| Gene ID |
100337125 (Bos taurus), 100683557 (Canis lupus familiaris), 101099202 (Felis catus), 102150816 (Equus caballus)
1834 (Homo sapiens), 25254 (Rattus norvegicus), 666279 (Mus musculus), 701581 (Macaca mulatta)
|
| Target Alternative Names |
DFNA39,DGI1,DMP3,DPP,DSP,DSPP,Dentin sialophosphoprotein,Dmp2,Dmp3,Dpp,Dsp,Dspp,RDSP2
|
| Uniprot Accession |
Q9NZW4,Q62598,P97399
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
ECM-receptor interaction
|
| Gene Ensembl |
ENSBTAG00000045714, ENSCAFG00845015696, ENSECAG00000007608, ENSG00000152591, ENSMUSG00000053268
|
DSPP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1834 | Pre-made Human DSPP/DPP/DSP siRNA oligo Duplex | 1834 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25254 | Pre-made Rat Dspp/Dsp/RDSP2 siRNA oligo Duplex | 25254 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo666279 | Pre-made Mouse Dspp/Dpp/Dsp siRNA oligo Duplex | 666279 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701581 | Pre-made Cynomolgus/Rhesus macaque DSPP siRNA oligo Duplex | 701581 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099202 | Pre-made Cat/Feline DSPP siRNA oligo Duplex | 101099202 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100683557 | Pre-made Dog/Canine DSPP siRNA oligo Duplex | 100683557 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100337125 | Pre-made Bovines/Cattle DSPP siRNA oligo Duplex | 100337125 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102150816 | Pre-made Equine/Horse DSPP siRNA oligo Duplex | 102150816 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DSPP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0895-Ab | Human | Anti-Human DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0895-Ab | Rat | Anti-Rat DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0895-Ab | Mouse | Anti-Mouse DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0895-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0895-Ab | Cat/Feline | Anti-Cat/Feline DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0895-Ab | Dog/Canine | Anti-Dog/Canine DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0895-Ab | Bovines/Cattle | Anti-Bovines/Cattle DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0895-Ab | Equine/Horse | Anti-Equine/Horse DSPP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
DSPP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0895-Ag | Human | Human DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0895-Ag | Rat | Rat DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0895-Ag | Mouse | Mouse DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0895-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0895-Ag | Cat/Feline | Cat/Feline DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0895-Ag | Dog/Canine | Dog/Canine DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0895-Ag | Bovines/Cattle | Bovines/Cattle DSPP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0895-Ag | Equine/Horse | Equine/Horse DSPP recombinant protein | Mammalian cell | Detail |
