Recombinant multi-species DEFB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEFB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
The Alternative Names of target: BD-1,BD1,Beta-defensin 1,CBD1,CDK4,DEFB-1,DEFB1,DEFB101,Defb1,Defensin,HBD1,RHBD-1,beta 1,hBD-1

Target products collectionGo to DEFB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0855-Ag-1/ GM-Tg-hg-SE0855-Ag-2 Human DEFB1 protein Human
GM-Tg-rg-SE0855-Ag-1/ GM-Tg-rg-SE0855-Ag-2 Rat DEFB1 protein Rat
GM-Tg-mg-SE0855-Ag-1/ GM-Tg-mg-SE0855-Ag-2 Mouse DEFB1 protein Mouse
GM-Tg-cynog-SE0855-Ag-1/ GM-Tg-cynog-SE0855-Ag-2 Cynomolgus/Rhesus macaque DEFB1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0855-Ag-1/ GM-Tg-felg-SE0855-Ag-2 Feline DEFB1 protein Feline
GM-Tg-cang-SE0855-Ag-1/ GM-Tg-cang-SE0855-Ag-2 Canine DEFB1 protein Canine
GM-Tg-bovg-SE0855-Ag-1/ GM-Tg-bovg-SE0855-Ag-2 Bovine DEFB1 protein Bovine
GM-Tg-equg-SE0855-Ag-1/ GM-Tg-equg-SE0855-Ag-2 Equine DEFB1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0855-Ag-1/ GM-Tg-hg-SE0855-Ag-2; GM-Tg-rg-SE0855-Ag-1/ GM-Tg-rg-SE0855-Ag-2;
GM-Tg-mg-SE0855-Ag-1/ GM-Tg-mg-SE0855-Ag-2; GM-Tg-cynog-SE0855-Ag-1/ GM-Tg-cynog-SE0855-Ag-2;
GM-Tg-felg-SE0855-Ag-1/ GM-Tg-felg-SE0855-Ag-2; GM-Tg-cang-SE0855-Ag-1/ GM-Tg-cang-SE0855-Ag-2;
GM-Tg-bovg-SE0855-Ag-1/ GM-Tg-bovg-SE0855-Ag-2; GM-Tg-equg-SE0855-Ag-1/ GM-Tg-equg-SE0855-Ag-2
Products Name DEFB1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DEFB1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEFB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.