Explore DEFB1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0855
|
| Target Name |
DEFB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1672
|
| Gene ID |
102150198 (Equus caballus), 102902220 (Felis catus), 1672 (Homo sapiens), 574187 (Macaca mulatta)
611241 (Canis lupus familiaris), 83687 (Rattus norvegicus)
|
| Target Alternative Names |
BD-1,BD1,Beta-defensin 1,CBD1,CDK4,DEFB-1,DEFB1,DEFB101,Defb1,Defensin,HBD1,RHBD-1,beta 1,hBD-1
|
| Uniprot Accession |
P60022,O18794,O89117
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Ovary Cancer, Contrast - Induced Nephropathy, Contact with and (suspected) exposure to arsenic, Kidney transplant rejection
|
| Disease from KEGG |
ABC transporters, Staphylococcus aureus infection
|
| Gene Ensembl |
ENSECAG00000034702, ENSG00000164825, ENSMMUG00000053229, ENSCAFG00845021822
|
Pre-made viral vector of DEFB1 cDNA Clones/ORF Plasmid
DEFB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1672 | Pre-made Human DEFB1/BD1/HBD1 siRNA oligo Duplex | 1672 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83687 | Pre-made Rat Defb1/CDK4 siRNA oligo Duplex | 83687 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574187 | Pre-made Cynomolgus/Rhesus macaque DEFB1/RHBD-1 siRNA oligo Duplex | 574187 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102902220 | Pre-made Cat/Feline DEFB1 siRNA oligo Duplex | 102902220 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611241 | Pre-made Dog/Canine DEFB1/CBD1 siRNA oligo Duplex | 611241 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102150198 | Pre-made Equine/Horse DEFB1 siRNA oligo Duplex | 102150198 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DEFB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0855-Ab | Human | Anti-Human DEFB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0855-Ab | Rat | Anti-Rat DEFB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0855-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DEFB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0855-Ab | Cat/Feline | Anti-Cat/Feline DEFB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0855-Ab | Dog/Canine | Anti-Dog/Canine DEFB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0855-Ab | Equine/Horse | Anti-Equine/Horse DEFB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
DEFB1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0855-Ag | Human | Human DEFB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0855-Ag | Rat | Rat DEFB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0855-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DEFB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0855-Ag | Cat/Feline | Cat/Feline DEFB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0855-Ag | Dog/Canine | Dog/Canine DEFB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0855-Ag | Equine/Horse | Equine/Horse DEFB1 recombinant protein | Mammalian cell | Detail |
