Recombinant multi-species DEFA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEFA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014]
The Alternative Names of target: DEF1,DEFA1,DEFA2,Defensin,HNP-1,HNP-1 (HP-1,HP-1,HP1,HP1),MRS,Neutrophil defensin 1,alpha 1

Target products collectionGo to DEFA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0849-Ag-1/ GM-Tg-hg-SE0849-Ag-2 Human DEFA1 protein Human
GM-Tg-rg-SE0849-Ag-1/ GM-Tg-rg-SE0849-Ag-2 Rat DEFA1 protein Rat
GM-Tg-mg-SE0849-Ag-1/ GM-Tg-mg-SE0849-Ag-2 Mouse DEFA1 protein Mouse
GM-Tg-cynog-SE0849-Ag-1/ GM-Tg-cynog-SE0849-Ag-2 Cynomolgus/Rhesus macaque DEFA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0849-Ag-1/ GM-Tg-felg-SE0849-Ag-2 Feline DEFA1 protein Feline
GM-Tg-cang-SE0849-Ag-1/ GM-Tg-cang-SE0849-Ag-2 Canine DEFA1 protein Canine
GM-Tg-bovg-SE0849-Ag-1/ GM-Tg-bovg-SE0849-Ag-2 Bovine DEFA1 protein Bovine
GM-Tg-equg-SE0849-Ag-1/ GM-Tg-equg-SE0849-Ag-2 Equine DEFA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0849-Ag-1/ GM-Tg-hg-SE0849-Ag-2; GM-Tg-rg-SE0849-Ag-1/ GM-Tg-rg-SE0849-Ag-2;
GM-Tg-mg-SE0849-Ag-1/ GM-Tg-mg-SE0849-Ag-2; GM-Tg-cynog-SE0849-Ag-1/ GM-Tg-cynog-SE0849-Ag-2;
GM-Tg-felg-SE0849-Ag-1/ GM-Tg-felg-SE0849-Ag-2; GM-Tg-cang-SE0849-Ag-1/ GM-Tg-cang-SE0849-Ag-2;
GM-Tg-bovg-SE0849-Ag-1/ GM-Tg-bovg-SE0849-Ag-2; GM-Tg-equg-SE0849-Ag-1/ GM-Tg-equg-SE0849-Ag-2
Products Name DEFA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DEFA1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEFA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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