Recombinant multi-species C-Reactive Protein/CRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine C-Reactive Protein/CRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
The Alternative Names of target: Aa1249,Ab1-341,Ab2-196,Ac1-114,Ac1262,Ac2-069,Ba2-693,C-Reactive Protein,C-reactive protein,CRP,Crp,PTX1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0824-Ag-1/ GM-Tg-hg-SE0824-Ag-2 | Human C-Reactive Protein/CRP protein | Human |
| GM-Tg-rg-SE0824-Ag-1/ GM-Tg-rg-SE0824-Ag-2 | Rat C-Reactive Protein/CRP protein | Rat |
| GM-Tg-mg-SE0824-Ag-1/ GM-Tg-mg-SE0824-Ag-2 | Mouse C-Reactive Protein/CRP protein | Mouse |
| GM-Tg-cynog-SE0824-Ag-1/ GM-Tg-cynog-SE0824-Ag-2 | Cynomolgus/Rhesus macaque C-Reactive Protein/CRP protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0824-Ag-1/ GM-Tg-felg-SE0824-Ag-2 | Feline C-Reactive Protein/CRP protein | Feline |
| GM-Tg-cang-SE0824-Ag-1/ GM-Tg-cang-SE0824-Ag-2 | Canine C-Reactive Protein/CRP protein | Canine |
| GM-Tg-bovg-SE0824-Ag-1/ GM-Tg-bovg-SE0824-Ag-2 | Bovine C-Reactive Protein/CRP protein | Bovine |
| GM-Tg-equg-SE0824-Ag-1/ GM-Tg-equg-SE0824-Ag-2 | Equine C-Reactive Protein/CRP protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0824-Ag-1/ GM-Tg-hg-SE0824-Ag-2;
GM-Tg-rg-SE0824-Ag-1/ GM-Tg-rg-SE0824-Ag-2;
GM-Tg-mg-SE0824-Ag-1/ GM-Tg-mg-SE0824-Ag-2; GM-Tg-cynog-SE0824-Ag-1/ GM-Tg-cynog-SE0824-Ag-2; GM-Tg-felg-SE0824-Ag-1/ GM-Tg-felg-SE0824-Ag-2; GM-Tg-cang-SE0824-Ag-1/ GM-Tg-cang-SE0824-Ag-2; GM-Tg-bovg-SE0824-Ag-1/ GM-Tg-bovg-SE0824-Ag-2; GM-Tg-equg-SE0824-Ag-1/ GM-Tg-equg-SE0824-Ag-2 |
| Products Name | C-Reactive Protein/CRP protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | C-Reactive Protein/CRP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine C-Reactive Protein/CRP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.