Recombinant multi-species C-Reactive Protein/CRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine C-Reactive Protein/CRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
The Alternative Names of target: Aa1249,Ab1-341,Ab2-196,Ac1-114,Ac1262,Ac2-069,Ba2-693,C-Reactive Protein,C-reactive protein,CRP,Crp,PTX1

Target products collectionGo to C-Reactive Protein/CRP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0824-Ag-1/ GM-Tg-hg-SE0824-Ag-2 Human C-Reactive Protein/CRP protein Human
GM-Tg-rg-SE0824-Ag-1/ GM-Tg-rg-SE0824-Ag-2 Rat C-Reactive Protein/CRP protein Rat
GM-Tg-mg-SE0824-Ag-1/ GM-Tg-mg-SE0824-Ag-2 Mouse C-Reactive Protein/CRP protein Mouse
GM-Tg-cynog-SE0824-Ag-1/ GM-Tg-cynog-SE0824-Ag-2 Cynomolgus/Rhesus macaque C-Reactive Protein/CRP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0824-Ag-1/ GM-Tg-felg-SE0824-Ag-2 Feline C-Reactive Protein/CRP protein Feline
GM-Tg-cang-SE0824-Ag-1/ GM-Tg-cang-SE0824-Ag-2 Canine C-Reactive Protein/CRP protein Canine
GM-Tg-bovg-SE0824-Ag-1/ GM-Tg-bovg-SE0824-Ag-2 Bovine C-Reactive Protein/CRP protein Bovine
GM-Tg-equg-SE0824-Ag-1/ GM-Tg-equg-SE0824-Ag-2 Equine C-Reactive Protein/CRP protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0824-Ag-1/ GM-Tg-hg-SE0824-Ag-2; GM-Tg-rg-SE0824-Ag-1/ GM-Tg-rg-SE0824-Ag-2;
GM-Tg-mg-SE0824-Ag-1/ GM-Tg-mg-SE0824-Ag-2; GM-Tg-cynog-SE0824-Ag-1/ GM-Tg-cynog-SE0824-Ag-2;
GM-Tg-felg-SE0824-Ag-1/ GM-Tg-felg-SE0824-Ag-2; GM-Tg-cang-SE0824-Ag-1/ GM-Tg-cang-SE0824-Ag-2;
GM-Tg-bovg-SE0824-Ag-1/ GM-Tg-bovg-SE0824-Ag-2; GM-Tg-equg-SE0824-Ag-1/ GM-Tg-equg-SE0824-Ag-2
Products Name C-Reactive Protein/CRP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name C-Reactive Protein/CRP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine C-Reactive Protein/CRP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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