Recombinant multi-species Osteocalcin/OCN/BGLAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Osteocalcin/OCN/BGLAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
The Alternative Names of target: BGLAP,BGP,Bglap,Bglap1,Bglap2,Bgp,Bgpr,Bgpra,Bone Gla protein (BGP),GLA,Gamma-carboxyglutamic acid-containing protein,OC,OCN,OG1,Osteocalcin,mOC-A

Target products collectionGo to Osteocalcin/OCN/BGLAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0683-Ag-1/ GM-Tg-hg-SE0683-Ag-2 Human Osteocalcin/OCN/BGLAP protein Human
GM-Tg-rg-SE0683-Ag-1/ GM-Tg-rg-SE0683-Ag-2 Rat Osteocalcin/OCN/BGLAP protein Rat
GM-Tg-mg-SE0683-Ag-1/ GM-Tg-mg-SE0683-Ag-2 Mouse Osteocalcin/OCN/BGLAP protein Mouse
GM-Tg-cynog-SE0683-Ag-1/ GM-Tg-cynog-SE0683-Ag-2 Cynomolgus/Rhesus macaque Osteocalcin/OCN/BGLAP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0683-Ag-1/ GM-Tg-felg-SE0683-Ag-2 Feline Osteocalcin/OCN/BGLAP protein Feline
GM-Tg-cang-SE0683-Ag-1/ GM-Tg-cang-SE0683-Ag-2 Canine Osteocalcin/OCN/BGLAP protein Canine
GM-Tg-bovg-SE0683-Ag-1/ GM-Tg-bovg-SE0683-Ag-2 Bovine Osteocalcin/OCN/BGLAP protein Bovine
GM-Tg-equg-SE0683-Ag-1/ GM-Tg-equg-SE0683-Ag-2 Equine Osteocalcin/OCN/BGLAP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0683-Ag-1/ GM-Tg-hg-SE0683-Ag-2; GM-Tg-rg-SE0683-Ag-1/ GM-Tg-rg-SE0683-Ag-2;
GM-Tg-mg-SE0683-Ag-1/ GM-Tg-mg-SE0683-Ag-2; GM-Tg-cynog-SE0683-Ag-1/ GM-Tg-cynog-SE0683-Ag-2;
GM-Tg-felg-SE0683-Ag-1/ GM-Tg-felg-SE0683-Ag-2; GM-Tg-cang-SE0683-Ag-1/ GM-Tg-cang-SE0683-Ag-2;
GM-Tg-bovg-SE0683-Ag-1/ GM-Tg-bovg-SE0683-Ag-2; GM-Tg-equg-SE0683-Ag-1/ GM-Tg-equg-SE0683-Ag-2
Products Name Osteocalcin/OCN/BGLAP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Osteocalcin/OCN/BGLAP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Osteocalcin/OCN/BGLAP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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