Explore Osteocalcin/OCN/BGLAP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
| Target ID |
GM-SE0683
|
| Target Name |
Osteocalcin/OCN/BGLAP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
632
|
| Gene ID |
101085947 (Felis catus), 12096 (Mus musculus), 25295 (Rattus norvegicus), 281646 (Bos taurus)
403762 (Canis lupus familiaris), 632 (Homo sapiens), 718296 (Macaca mulatta)
|
| Target Alternative Names |
BGLAP,BGP,Bglap,Bglap1,Bglap2,Bgp,Bgpr,Bgpra,Bone Gla protein (BGP),GLA,Gamma-carboxyglutamic acid-containing protein,OC,OCN,OG1,Osteocalcin,mOC-A
|
| Uniprot Accession |
P86546,P04640,P02820,P81455,P02818,A2D670
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Breast Cancer, bone formation, Disturbances in bone turnover, glucocorticoid-induced osteopenia, growth
|
| Disease from KEGG |
Parathyroid hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSMUSG00000074483, ENSCAFG00845009909, ENSG00000242252, ENSMMUG00000004902
|
Pre-made viral vector of Osteocalcin/OCN/BGLAP cDNA Clones/ORF Plasmid
Osteocalcin/OCN/BGLAP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo632 | Pre-made Human BGLAP/OC/BGP siRNA oligo Duplex | 632 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25295 | Pre-made Rat Bglap/Bgp/Bgpr siRNA oligo Duplex | 25295 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12096 | Pre-made Mouse Bglap/OC/BGP siRNA oligo Duplex | 12096 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718296 | Pre-made Cynomolgus/Rhesus macaque BGLAP siRNA oligo Duplex | 718296 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085947 | Pre-made Cat/Feline BGLAP/BGP siRNA oligo Duplex | 101085947 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403762 | Pre-made Dog/Canine BGLAP/BGP/GLA siRNA oligo Duplex | 403762 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281646 | Pre-made Bovines/Cattle BGLAP/BGP siRNA oligo Duplex | 281646 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
Osteocalcin/OCN/BGLAP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0683-Ab | Human | Anti-Human Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0683-Ab | Rat | Anti-Rat Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0683-Ab | Mouse | Anti-Mouse Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0683-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0683-Ab | Cat/Feline | Anti-Cat/Feline Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0683-Ab | Dog/Canine | Anti-Dog/Canine Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0683-Ab | Bovines/Cattle | Anti-Bovines/Cattle Osteocalcin/OCN/BGLAP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Osteocalcin/OCN/BGLAP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0683-Ag | Human | Human Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0683-Ag | Rat | Rat Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0683-Ag | Mouse | Mouse Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0683-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0683-Ag | Cat/Feline | Cat/Feline Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0683-Ag | Dog/Canine | Dog/Canine Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0683-Ag | Bovines/Cattle | Bovines/Cattle Osteocalcin/OCN/BGLAP recombinant protein | Mammalian cell | Detail |
