Recombinant multi-species AMH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
The Alternative Names of target: AMH,Amh,Anti-Muellerian hormone (AMH),MIF,MIS,Mis,Muellerian-inhibiting factor,Muellerian-inhibiting substance (MIS)

Target products collectionGo to AMH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0660-Ag-1/ GM-Tg-hg-SE0660-Ag-2 Human AMH protein Human
GM-Tg-rg-SE0660-Ag-1/ GM-Tg-rg-SE0660-Ag-2 Rat AMH protein Rat
GM-Tg-mg-SE0660-Ag-1/ GM-Tg-mg-SE0660-Ag-2 Mouse AMH protein Mouse
GM-Tg-cynog-SE0660-Ag-1/ GM-Tg-cynog-SE0660-Ag-2 Cynomolgus/Rhesus macaque AMH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0660-Ag-1/ GM-Tg-felg-SE0660-Ag-2 Feline AMH protein Feline
GM-Tg-cang-SE0660-Ag-1/ GM-Tg-cang-SE0660-Ag-2 Canine AMH protein Canine
GM-Tg-bovg-SE0660-Ag-1/ GM-Tg-bovg-SE0660-Ag-2 Bovine AMH protein Bovine
GM-Tg-equg-SE0660-Ag-1/ GM-Tg-equg-SE0660-Ag-2 Equine AMH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0660-Ag-1/ GM-Tg-hg-SE0660-Ag-2; GM-Tg-rg-SE0660-Ag-1/ GM-Tg-rg-SE0660-Ag-2;
GM-Tg-mg-SE0660-Ag-1/ GM-Tg-mg-SE0660-Ag-2; GM-Tg-cynog-SE0660-Ag-1/ GM-Tg-cynog-SE0660-Ag-2;
GM-Tg-felg-SE0660-Ag-1/ GM-Tg-felg-SE0660-Ag-2; GM-Tg-cang-SE0660-Ag-1/ GM-Tg-cang-SE0660-Ag-2;
GM-Tg-bovg-SE0660-Ag-1/ GM-Tg-bovg-SE0660-Ag-2; GM-Tg-equg-SE0660-Ag-1/ GM-Tg-equg-SE0660-Ag-2
Products Name AMH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AMH
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.